UMIN-ICDS Clinical Trial

Public title

Development of a Visual Associative Memory Assessment Task: A Preliminary Investigation of Task Characteristics and Validity

Acronym

Visual Associative Memory Assessment Task Study

Scientific Title

Development of a Visual Associative Memory Assessment Task: A Preliminary Investigation of Task Characteristics and Validity

Scientific Title:Acronym

Visual Associative Memory Assessment Task Study

Region

Japan

Condition

Healthy subjects

Classification by specialty

Adult

Classification by malignancy

Others

Genomic information

NO

Narrative objectives1

This study aims to develop a visual associative memory assessment task using color-number associations and to (1) examine task difficulty and measurement characteristics by analyzing changes in accuracy and score distributions with increasing memory load, and (2) preliminarily evaluate its construct validity by examining associations between task performance and established neuropsychological test measures.

Basic objectives2

Efficacy

Basic objectives -Others

Trial characteristics_1

Trial characteristics_2

Developmental phase

Primary outcomes

Changes in Task Performance and Score Distributions

Key secondary outcomes

Associations Between Task Performance and Established Neuropsychological Test Scores

Study type

Interventional

Basic design

Single arm

Randomization

Non-randomized

Randomization unit

Blinding

Open -no one is blinded

Control

Uncontrolled

Stratification

Dynamic allocation

Institution consideration

Blocking

Concealment

No. of arms

1

Purpose of intervention

Prevention

Type of intervention

Other

Interventions/Control_1

All participants will complete a computer-based visual associative memory task. Participants will be required to memorize sequentially presented color-number associations and subsequently identify the number corresponding to a cued color. Memory load will be manipulated by varying the number of color-number associations, with three difficulty levels consisting of three, four, or five associations. At each difficulty level, participants will complete three sets of 10 trials, resulting in 30 trials per difficulty level and 90 trials in total. Each stimulus will be presented for 1,250 ms, with an interstimulus interval of 250 ms.

Interventions/Control_2

Interventions/Control_3

Interventions/Control_4

Interventions/Control_5

Interventions/Control_6

Interventions/Control_7

Interventions/Control_8

Interventions/Control_9

Interventions/Control_10

Age-lower limit

18

years-old

<=

Age-upper limit

35

years-old

>

Gender

Male and Female

Key inclusion criteria

1. Healthy adults aged 18 years or older and younger than 35 years.

2. Right-handed individuals.

3. Individuals without neurological or psychiatric disorders.

4. Individuals who have received sufficient information about the study and provided written informed consent to participate voluntarily.

Key exclusion criteria

Individuals with a history of neurological or psychiatric disorders.

Individuals with a history of head injury accompanied by loss of consciousness.

Individuals currently taking medications that affect the central nervous system.

Individuals with visual or hearing impairments, or those who are unable to complete the neuropsychological tests used in this study for other reasons.

Individuals deemed unsuitable for participation by the principal investigator.

Target sample size

40

Name of lead principal investigator

1st name	Daisuke
Middle name
Last name	Sawamura

Organization

Hokkaido University

Division name

Division of Rehabilitation Science

Zip code

0600812

Address

Kita 12-jo Nishi 5-chome, Kita-ku, Sapporo, Hokkaido, Japan

TEL

0117063387

Email

d.sawamura@pop.med.hokudai.ac.jp

Name of contact person

1st name	Daisuke
Middle name
Last name	Sawamura

Organization

Faculty of Health Sciences, Hokkaido University, Japan

Division name

Division of Rehabilitation Science

Zip code

0600812

Address

Kita 12-jo Nishi 5-chome, Kita-ku, Sapporo, Hokkaido, Japan

TEL

0117063387

Homepage URL

Email

d.sawamura@pop.med.hokudai.ac.jp

Institute

Hokkaido University

Institute

Department

Personal name

Daisuke Sawamura

Organization

Japan Science and Technology Agency

Organization

Division

Category of Funding Organization

Japanese Governmental office

Nationality of Funding Organization

Japan

Co-sponsor

Name of secondary funder(s)

Organization

Faculty of Health Sciences, Graduate School of Health Sciences, Hokkaido University

Address

Kita 12-jo Nishi 5-chome , Kita-ku, Sapporo, Hokkaido, Japan

Tel

0117063387

Email

d.sawamura@pop.med.hokudai.ac.jp

Secondary IDs

NO

Study ID_1

Org. issuing International ID_1

Study ID_2

Org. issuing International ID_2

IND to MHLW

Institutions

Date of disclosure of the study information

2026

Year

10

Month

13

Day

URL releasing protocol

Publication of results

Unpublished

URL related to results and publications

Number of participants that the trial has enrolled

Results

Results date posted

Results Delayed

Results Delay Reason

Date of the first journal publication of results

Baseline Characteristics

Participant flow

Adverse events

Outcome measures

Plan to share IPD

IPD sharing Plan description

Recruitment status

Preinitiation

Date of protocol fixation

2026

Year

10

Month

13

Day

Date of IRB

Anticipated trial start date

2026

Year

11

Month

13

Day

Last follow-up date

2028

Year

03

Month

31

Day

Date of closure to data entry

Date trial data considered complete

Date analysis concluded

Other related information

Registered date

2026

Year

10

Month

13

Day

Last modified on

2026

Year

10

Month

13

Day

Link to view the page

Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000072404