UMIN-ICDS Clinical Trial
| Unique ID issued by UMIN | UMIN000062599 |
|---|---|
| Receipt number | R000071551 |
| Scientific Title | Effects of hop supplementation on muscle damage, inflammatory response, and recovery of muscle function following resistance evercise. |
| Date of disclosure of the study information | 2026/08/18 |
| Last modified on | 2026/08/18 11:03:20 |
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Basic information
Public title
Effect of supplementation on recovery of muscle fatigue
Acronym
Effect of supplementation on recovery of muscle fatigue
Scientific Title
Effects of hop supplementation on muscle damage, inflammatory response, and recovery of muscle function following resistance evercise.
Scientific Title:Acronym
Effect of supplementation on recovery of muscle fatigue
Region
| Japan |
Condition
Condition
Healthy adult
Classification by specialty
| Not applicable | Adult |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
To evaluate the effects of hop supplementation on muscle damage, inflammatory responses, and the recovery of muscle function following resistance training
Basic objectives2
Efficacy
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Blood Myoglobin, Urinary 3Methylhistidine
Key secondary outcomes
Growth Hormone, Free Testosterone, Cortisol, Blood Glucose, Muscle Thickness, Maximum Muscle Strength, Muscle Power, VAS (Fatigue, Muscle Swelling, Muscle Soreness, HR, BP)
Base
Study type
Interventional
Study design
Basic design
Cross-over
Randomization
Randomized
Randomization unit
Individual
Blinding
Double blind -all involved are blinded
Control
Placebo
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
2
Purpose of intervention
Prevention
Type of intervention
| Food |
Interventions/Control_1
Daily intake of hop supplementation for 2 weeks - Washout - Daily intake of placebo for 2 weeks
Interventions/Control_2
Daily intake of placebo for 2 weeks - Washout - Daily intake of hop supplementation for 2 weeks
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 18 | years-old | <= |
Age-upper limit
| 27 | years-old | >= |
Gender
Male and Female
Key inclusion criteria
1.Individuals aged 18 or higher and less than 27 years old.
2.Individuals who are ability to perform resistance training trial.
3.Individuals who have providec prior infomed consent.
Key exclusion criteria
1.Individuals diagnosed with medical conditions for which exercise is absolutely contraindicated.
2.Individuals with metabolic, respiratory, cardiovascular, or coagulation disorders, or those who have been advised by a physician to avoid high-intensity exercise.
3.Individuals with orthopedic conditions affecting the lower extremities that may interfere with resistance exercise.
4.Individuals currently taking medication or habitually consuming dietary supplements.
5.Individuals with allergies to the test food (including soybeans, hops, hop-derived products, or any other ingredients contained in the test food).
6.Individuals with irregular menstrual cycles or those using oral contraceptives.
7.Individuals who are pregnant, may be pregnant, are planning to become pregnant, or are breastfeeding.
8.Individuals for whom study measurements may be difficult to perform (including women with irregular menstrual cycles).
Target sample size
20
Research contact person
Name of lead principal investigator
| 1st name | Kazushige |
| Middle name | |
| Last name | Goto |
Organization
Ritsumeikan University
Division name
Faculty of Sport and Health Science
Zip code
525-8577
Address
1-1-1, Noji-higashi, Kusatsu, Shiga, Japan
TEL
077-599-4127
kagoto@fc.ritsumei.ac.jp
Public contact
Name of contact person
| 1st name | Kazushige |
| Middle name | |
| Last name | Goto |
Organization
Ritsumeikan University
Division name
Faculty of Sport and Health Science
Zip code
525-8577
Address
1-1-1, Noji-higashi, Kusatus, Shiga, Japan
TEL
077-599-4127
Homepage URL
kagoto@fc.ritsumei.ac.jp
Sponsor or person
Institute
Ritsumeikan University
Faculty of Sport and Health Science
Institute
Department
Personal name
Funding Source
Organization
DAICEL Corporation
Organization
Division
Category of Funding Organization
Profit organization
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Ritsumeikan University
Address
1, Suzakucho, Nishinokyo, Nakagyo-ku, Kyoto, Japan
Tel
N/A
N/A
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
立命館大学スポーツ健康科学部（滋賀県）
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 08 | Month | 18 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Preinitiation
Date of protocol fixation
| 2026 | Year | 08 | Month | 04 | Day |
Date of IRB
| 2026 | Year | 08 | Month | 04 | Day |
Anticipated trial start date
| 2026 | Year | 08 | Month | 14 | Day |
Last follow-up date
| 2026 | Year | 12 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
Management information
Registered date
| 2026 | Year | 08 | Month | 18 | Day |
Last modified on
| 2026 | Year | 08 | Month | 18 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000071551
