UMIN-ICDS Clinical Trial
| Unique ID issued by UMIN | UMIN000062342 |
|---|---|
| Receipt number | R000071347 |
| Scientific Title | Effects of bilberry-derived anthocyanins on accommodative function and ocular fatigue: a systematic review |
| Date of disclosure of the study information | 2026/08/01 |
| Last modified on | 2026/07/27 09:18:57 |
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Basic information
Public title
Effects of bilberry-derived anthocyanins on accommodative function and ocular fatigue: a systematic review
Acronym
Bilberry anthocyanins and eye function SR
Scientific Title
Effects of bilberry-derived anthocyanins on accommodative function and ocular fatigue: a systematic review
Scientific Title:Acronym
Bilberry anthocyanins for accommodative function and ocular fatigue SR
Region
| Japan |
Condition
Condition
Decreased accommodative function and ocular fatigue associated with visual display terminal tasks
Classification by specialty
| Ophthalmology |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
To comprehensively identify and evaluate existing randomized controlled trials on the effects of oral intake of bilberry-derived anthocyanins on human accommodative function and ocular fatigue, and to summarize the scientific evidence from the perspective of the totality of evidence.
Basic objectives2
Efficacy
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Accommodative function and ocular fatigue
Key secondary outcomes
Base
Study type
Others,meta-analysis etc
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 18 | years-old | <= |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
P (Participant): Healthy adult men and women, or adults with subjective ocular fatigue.
I (Intervention): Oral intake of food containing bilberry-derived anthocyanins. The dosage, duration of intake, dosage form, and follow-up period are not restricted.
C (Comparison): Placebo foods.
O (Outcome): Accommodative function and ocular fatigue.
S (Study Design): Randomized parallel-group controlled trials and randomized crossover trials.
Key exclusion criteria
Studies that do not meet the PICO criteria will be excluded. Conference abstracts, conference proceedings, reviews, commentaries, case reports, and other publication types with insufficient information for evaluation will be excluded.
Target sample size
Research contact person
Name of lead principal investigator
| 1st name | Naomichi |
| Middle name | |
| Last name | Machida |
Organization
Omnica Co., Ltd
Division name
Sales Administration Division
Zip code
173-0004
Address
4-21-7 Itabashi, Itabashi-ku, Tokyo, Japan.
TEL
03-5844-4202
machida@omnica.co.jp
Public contact
Name of contact person
| 1st name | Naomichi |
| Middle name | |
| Last name | Machida |
Organization
Omnica Co., Ltd
Division name
Sales Administration Division
Zip code
173-0004
Address
4-21-7 Itabashi, Itabashi-ku, Tokyo, Japan.
TEL
03-5844-4202
Homepage URL
machida@omnica.co.jp
Sponsor or person
Institute
Omnica Co.,Ltd
Institute
Department
Personal name
Funding Source
Organization
Omnica Co.,Ltd
Organization
Division
Category of Funding Organization
Profit organization
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Not applicable
Address
Not applicable
Tel
03-5844-4202
machida@omnica.co.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 08 | Month | 01 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Preinitiation
Date of protocol fixation
| 2026 | Year | 07 | Month | 25 | Day |
Date of IRB
Anticipated trial start date
| 2026 | Year | 08 | Month | 03 | Day |
Last follow-up date
| 2026 | Year | 12 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
This SR will be conducted in accordance with PRISMA 2020
Management information
Registered date
| 2026 | Year | 07 | Month | 27 | Day |
Last modified on
| 2026 | Year | 07 | Month | 27 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000071347
