UMIN-ICDS Clinical Trial
| Unique ID issued by UMIN | UMIN000063207 |
|---|---|
| Receipt number | R000071325 |
| Scientific Title | Evaluation Study on Improvement of Canine Dementia by Intake of Plasma Collagen Derived from Chicken Breast |
| Date of disclosure of the study information | 2026/10/07 |
| Last modified on | 2026/10/07 16:18:01 |
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Basic information
Public title
Evaluation Study on Improvement of Canine Dementia by Intake of Plasma Collagen Derived from Chicken Breast
Acronym
Evaluation Study on Improvement of Canine Dementia by Intake of Plasma Collagen
Scientific Title
Evaluation Study on Improvement of Canine Dementia by Intake of Plasma Collagen Derived from Chicken Breast
Scientific Title:Acronym
Evaluation Study on Improvement of Canine Dementia by Intake of Plasma Collagen
Region
| Japan |
Condition
Condition
Canine Dementia
Classification by specialty
| Not applicable | Adult |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
In elderly small dogs, we examine whether an 18-week intake of chicken breast-derived plasma rosa improves the dementia score (CCDR).
Basic objectives2
Safety,Efficacy
Basic objectives -Others
Trial characteristics_1
Confirmatory
Trial characteristics_2
Others
Developmental phase
Phase I,II
Assessment
Primary outcomes
Change in CCDR (Canine Cognitive Dysfunction Rating) score from baseline to week 18
Key secondary outcomes
NAD CRP and beta amyloidrelated blood biomarkers
Base
Study type
Interventional
Study design
Basic design
Parallel
Randomization
Randomized
Randomization unit
Cluster
Blinding
Double blind -all involved are blinded
Control
Placebo
Stratification
YES
Dynamic allocation
YES
Institution consideration
Institution is not considered as adjustment factor.
Blocking
YES
Concealment
Central registration
Intervention
No. of arms
2
Purpose of intervention
Treatment
Type of intervention
| Food |
Interventions/Control_1
Plasmalogen 1mg + Maltose 1g (powder, individually packaged 1g)
Interventions/Control_2
Maltose 1g (powder, non-individually packaged: serve in portions of total amount)
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 10 | years-old | < |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
Dogs aged 10 years or older and weighing 10 kg or less (excluding brachycephalic breeds)
Owners can understand the explanation and obtain written consent
Cognitive decline is suspected by the veterinarian, and CCDR evaluation is possible
Continuous intake for 18 weeks, home visit evaluation, and blood collection available
During the exam period, there is no intention to make significant changes to the living environment (diet, exercise, living conditions).
Key exclusion criteria
Uncontrolled underlying conditions such as severe heart, kidney, liver disease, and endocrine disorders
Frequent convulsive seizures and severe pain make behavior assessment difficult.
Newly initiated or recent dosage changes of treatments/supplements that may affect cognitive function (duration fixed by operation)
If the principal veterinarian deems it inappropriate
Target sample size
10
Research contact person
Name of lead principal investigator
| 1st name | Sigerori |
| Middle name | |
| Last name | Nibun |
Organization
EAS Corporation
Division name
Development Department
Zip code
231-0062
Address
10F, Hulic Minatomirai, 1-1-7 Sakuragicho, Naka-ku, Yokohama, Kanagawa 231-0062, Japan
TEL
0453743392
info@eas-ct.jp
Public contact
Name of contact person
| 1st name | Shigerori |
| Middle name | |
| Last name | nibun |
Organization
EAS Corporation
Division name
Development Department
Zip code
231-0062
Address
10F, Hulic Minatomirai, 1-1-7 Sakuragicho, Naka-ku, Yokohama, Kanagawa 231-0062, Japan
TEL
0453743392
Homepage URL
https://eas-ct.jp/
info@eas-ct.jp
Sponsor or person
Institute
EAS
Institute
Department
Personal name
Funding Source
Organization
MARUDAI FOOD CO., LTD.
Organization
Division
Category of Funding Organization
Profit organization
Nationality of Funding Organization
Japan
Other related organizations
Co-sponsor
Okayama University of Science
Name of secondary funder(s)
IRB Contact (For public release)
Organization
EAS
Address
10F, Hulic Minatomirai, 1-1-7 Sakuragicho, Naka-ku, Yokohama, Kanagawa 231-0062, Japan
Tel
0453743392
info@eas-ct.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 10 | Month | 07 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Open public recruiting
Date of protocol fixation
| 2026 | Year | 09 | Month | 01 | Day |
Date of IRB
| 2026 | Year | 09 | Month | 15 | Day |
Anticipated trial start date
| 2026 | Year | 10 | Month | 07 | Day |
Last follow-up date
| 2027 | Year | 05 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
Management information
Registered date
| 2026 | Year | 10 | Month | 07 | Day |
Last modified on
| 2026 | Year | 10 | Month | 07 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000071325
