UMIN-ICDS Clinical Trial
| Unique ID issued by UMIN | UMIN000062028 |
|---|---|
| Receipt number | R000070977 |
| Scientific Title | Characterization of the temporo-parietal junction using multimodal brain imaging and its application to perceptual learning |
| Date of disclosure of the study information | 2026/06/24 |
| Last modified on | 2026/06/23 13:57:00 |
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Basic information
Public title
Characterization of the temporo-parietal junction using multimodal brain imaging and its application to perceptual learning
Acronym
TPJ and somatosensory function
Scientific Title
Characterization of the temporo-parietal junction using multimodal brain imaging and its application to perceptual learning
Scientific Title:Acronym
TPJ and somatosensory function
Region
| Japan |
Condition
Condition
Healthy adults
Classification by specialty
| Adult |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
To clarify the relationship between somatosensory function (two-point discrimination) and gray matter volume, neurotransmitter (e.g., GABA) concentration, white matter microstructure, and functional networks centered on the temporo-parietal junction (TPJ).
Basic objectives2
Others
Basic objectives -Others
Investigation of the association between brain structural/functional measures and somatosensory function (observational)
Trial characteristics_1
Exploratory
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Two-point discrimination threshold (index of somatosensory function)
Key secondary outcomes
Gray matter volume around the TPJ, neurotransmitter (e.g., GABA) concentration, white matter microstructure, and functional network measures
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 18 | years-old | <= |
Age-upper limit
| 35 | years-old | >= |
Gender
Male and Female
Key inclusion criteria
Healthy adults aged 18-35 years who can understand the explanation of the experiment and provide voluntary written informed consent.
Key exclusion criteria
History of neurological disease (e.g., stroke, epilepsy) or psychiatric disease (e.g., depression, schizophrenia); use of drugs affecting the central nervous system; claustrophobia; metal implants in the body; pregnancy; any item applicable on the MRI screening questionnaire.
Target sample size
65
Research contact person
Name of lead principal investigator
| 1st name | HIDEAKI |
| Middle name | |
| Last name | ONISHI |
Organization
Niigata University of Health and Welfare
Division name
Faculty of Rehabilitation, Department of Physical Therapy
Zip code
950-3198
Address
1398, Shimami, Kita-ku, Niigata-City, 950-3198, Japan
TEL
025-257-4449
onishi@nuhw.ac.jp
Public contact
Name of contact person
| 1st name | HIDEAKI |
| Middle name | |
| Last name | ONISHI |
Organization
Niigata University of Health and Welfare
Division name
Faculty of Rehabilitation, Department of Physical Therapy
Zip code
950-3198
Address
1398, Shimami, Kita-ku, Niigata-City, 950-3198, Japan
TEL
025-257-4449
Homepage URL
onishi@nuhw.ac.jp
Sponsor or person
Institute
Niigata University of Health and Welfare
Institute
Department
Personal name
Onishi Hideaki
Funding Source
Organization
Japan Society for the Promotion of Science / MEXT (KAKENHI)
Organization
Division
Category of Funding Organization
Japanese Governmental office
Nationality of Funding Organization
JAPAN
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Niigata University of Health and Welfare
Address
1398, Shimami, Kita-ku, Niigata-City, 950-3198, Japan
Tel
025-257-4449
onishi@nuhw.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
新潟医療福祉大学（新潟県）
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 06 | Month | 24 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Preinitiation
Date of protocol fixation
| 2026 | Year | 04 | Month | 16 | Day |
Date of IRB
| 2026 | Year | 06 | Month | 09 | Day |
Anticipated trial start date
| 2026 | Year | 06 | Month | 24 | Day |
Last follow-up date
| 2028 | Year | 03 | Month | 31 | Day |
Date of closure to data entry
| 2029 | Year | 03 | Month | 31 | Day |
Date trial data considered complete
Date analysis concluded
Other
Other related information
This is a cross-sectional observational study in healthy adults. We examine the associations between somatosensory function (two-point discrimination threshold) as the outcome and gray matter volume, neurotransmitter (e.g., GABA) concentration, white matter microstructure, and functional networks centered on the temporo-parietal junction (TPJ) as factors. Data are collected prospectively. Sampling is convenience sampling from a defined population; no group allocation, randomization, or blinding is performed.
Management information
Registered date
| 2026 | Year | 06 | Month | 23 | Day |
Last modified on
| 2026 | Year | 06 | Month | 23 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000070977
