UMIN-ICDS Clinical Trial
| Unique ID issued by UMIN | UMIN000061977 |
|---|---|
| Receipt number | R000070919 |
| Scientific Title | Effects of Running Speed and Foot Strike Pattern on Anterior Cruciate Ligament Loading: A Cross-Sectional Study Using Three-Dimensional Motion Analysis |
| Date of disclosure of the study information | 2026/06/19 |
| Last modified on | 2026/06/19 15:08:00 |
* This page includes information on clinical trials registered in UMIN clinical trial registed system.
* We don't aim to advertise certain products or treatments
Basic information
Public title
Effects of running speed and foot strike pattern on knee ligament loading
Acronym
Run-ACL study
Scientific Title
Effects of Running Speed and Foot Strike Pattern on Anterior Cruciate Ligament Loading: A Cross-Sectional Study Using Three-Dimensional Motion Analysis
Scientific Title:Acronym
RSFS-ACL Study
Region
| Japan |
Condition
Condition
Healthy adults
Classification by specialty
| Adult |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
The purpose of this study is to investigate the effects of different running speeds and foot strike patterns (rearfoot strike, midfoot strike, and forefoot strike) on lower-extremity biomechanical variables associated with anterior cruciate ligament (ACL) loading in healthy adults.
Running biomechanics will be assessed using a three-dimensional motion analysis system and force plates. Biomechanical variables, including knee joint angles, joint moments, and ground reaction forces, will be calculated. By comparing these variables across different running speeds and foot strike patterns, this study aims to identify mechanical characteristics associated with ACL injury risk and to provide evidence that may contribute to the prevention of primary ACL injuries and secondary ACL reinjuries.
Basic objectives2
Others
Basic objectives -Others
To investigate the effects of different combinations of running speeds and foot strike patterns on lower-extremity kinematic and kinetic variables, including those of the hip, knee, and ankle joints, and to comprehensively evaluate biomechanical characteristics associated with ACL loading.
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Primary Outcome Measures
Peak vertical ground reaction force
Peak knee extension moment
Knee flexion angle
Knee valgus moment
Knee valgus angle
Hip adduction angle
These variables will be measured using a three-dimensional motion analysis system and force plates during running and will be compared across different running speeds and foot strike patterns.
Key secondary outcomes
Peak vertical ground reaction force
Knee flexion angle
Knee valgus moment
Knee valgus angle
Hip adduction angle
These variables will be measured using a three-dimensional motion analysis system and force plates during running and will be compared across different running speeds and foot strike patterns.
Base
Study type
Interventional
Study design
Basic design
Single arm
Randomization
Non-randomized
Randomization unit
Blinding
Open -no one is blinded
Control
Self control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
1
Purpose of intervention
Educational,Counseling,Training
Type of intervention
| Other |
Interventions/Control_1
Participants will perform running trials under different running speed conditions (2.5 m/s, 3.5 m/s, and 4.5 m/s) and foot strike pattern conditions (rearfoot strike, midfoot strike, and forefoot strike) in a laboratory equipped with a three-dimensional motion capture system and force plates. Running biomechanics will be assessed using a motion capture system, force plates, and photocells. Lower-extremity kinematic and kinetic data will be collected during running. Outcome measures will include peak vertical ground reaction force, peak knee extension moment, knee flexion angle, knee valgus moment, knee valgus angle, and hip adduction angle. These variables will be compared across running speed and foot strike conditions.
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 18 | years-old | <= |
Age-upper limit
| 30 | years-old | >= |
Gender
Male and Female
Key inclusion criteria
Healthy adults with no history of lower-extremity surgery and no current lower-extremity pain, injury, functional impairment, or physical condition that may affect running performance at the time of testing.
Key exclusion criteria
History of neurological or orthopedic disorders.
Any medical condition that may affect running biomechanics or performance.
Physical illness or poor health condition on the day of testing.
Inability to perform the instructed foot strike patterns during the running trials.
Target sample size
20
Research contact person
Name of lead principal investigator
| 1st name | Tomoya |
| Middle name | |
| Last name | Takabayashi |
Organization
Niigata University of Health and Welfare
Division name
Department of Physical Therapy, School of Rehabilitation Sciences
Zip code
950-3198
Address
1398 Shimami-cho, Kita-ku, Niigata City, Niigata, Japan
TEL
025-257-4455
takabayashi@nuhw.ac.jp
Public contact
Name of contact person
| 1st name | Tomoya |
| Middle name | |
| Last name | Takabayashi |
Organization
Niigata University of Health and Welfare
Division name
Department of Physical Therapy, School of Rehabilitation Sciences
Zip code
950-3198
Address
1398 Shimami-cho, Kita-ku, Niigata City, Niigata, Japan
TEL
025-257-4455
Homepage URL
takabayashi@nuhw.ac.jp
Sponsor or person
Institute
Niigata University of Health and Welfare
Institute
Department
Personal name
Funding Source
Organization
nothing
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Niigata University of Health and Welfare
Address
1398 Shimami-cho, Kita-ku, Niigata City, Niigata, Japan
Tel
025-257-4455
takabayashi@nuhw.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 06 | Month | 19 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Preinitiation
Date of protocol fixation
| 2026 | Year | 08 | Month | 01 | Day |
Date of IRB
Anticipated trial start date
| 2026 | Year | 08 | Month | 01 | Day |
Last follow-up date
| 2030 | Year | 09 | Month | 01 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
Management information
Registered date
| 2026 | Year | 06 | Month | 19 | Day |
Last modified on
| 2026 | Year | 06 | Month | 19 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000070919
