UMIN-ICDS Clinical Trial
| Unique ID issued by UMIN | UMIN000061711 |
|---|---|
| Receipt number | R000070620 |
| Scientific Title | Effects of gamma transcranial alternating current stimulation over the posterior parietal cortex on episodic memory retention following semantic exposure |
| Date of disclosure of the study information | 2026/05/27 |
| Last modified on | 2026/05/27 22:21:46 |
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Basic information
Public title
Effects of gamma transcranial alternating current stimulation over the posterior parietal cortex on episodic memory retention following semantic exposure
Acronym
Effects of gamma transcranial alternating current stimulation over the posterior parietal cortex on episodic memory retention following semantic exposure
Scientific Title
Effects of gamma transcranial alternating current stimulation over the posterior parietal cortex on episodic memory retention following semantic exposure
Scientific Title:Acronym
Effects of gamma transcranial alternating current stimulation over the posterior parietal cortex on episodic memory retention following semantic exposure
Region
| Japan |
Condition
Condition
Health adults
Classification by specialty
| Adult |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
To investigate whether gamma-band (40 Hz) transcranial alternating current stimulation (tACS) applied bilaterally over the posterior parietal cortex immediately after learning modulates the long-term retention and memory stabilization processes of initially learned episodic memories under conditions of exposure to semantically related subsequent information.
Basic objectives2
Efficacy
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Memory performance will be evaluated 28 days after transcranial alternating current stimulation (tACS).
Outcome measure: recognition task performance (d-prime).
Key secondary outcomes
Base
Study type
Interventional
Study design
Basic design
Parallel
Randomization
Randomized
Randomization unit
Individual
Blinding
Double blind -all involved are blinded
Control
Placebo
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
3
Purpose of intervention
Treatment
Type of intervention
| Maneuver |
Interventions/Control_1
Gamma (40 Hz) transcranial alternating current stimulation over the bilateral posterior parietal cortices
Interventions/Control_2
1Hz transcranial alternating current stimulation over the bilateral posterior parietal cortices
Interventions/Control_3
Sham stimulation of posterior parietal cortices
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 18 | years-old | <= |
Age-upper limit
| 25 | years-old | >= |
Gender
Male and Female
Key inclusion criteria
Native Japanese speakers, non-smokers, and right-handed individuals with normal or corrected-to-normal vision and no history of neurological injury or psychiatric disorders.
Key exclusion criteria
Individuals with a history of severe head injury, metallic implants in the head, epileptic seizures, skin disorders around the stimulation site, or the use of psychotropic medications will be excluded.
Target sample size
60
Research contact person
Name of lead principal investigator
| 1st name | Kenta |
| Middle name | |
| Last name | Honma |
Organization
Niigata University of Health and Welfare
Division name
Faculty of Rehabilitation, Department of Occupational Therapy
Zip code
0252574437
Address
1398 Shimamicho, Kita-ku, Niigata City, Niigata Prefecture
TEL
0252574437
kenta-honma@nuhw.ac.jp
Public contact
Name of contact person
| 1st name | Kenta |
| Middle name | |
| Last name | Honma |
Organization
Niigata University of Health and Welfare
Division name
Faculty of Rehabilitation, Department of Occupational Therapy
Zip code
950-3198
Address
1398 Shimamicho, Kita-ku, Niigata City, Niigata Prefecture
TEL
0252574437
Homepage URL
kenta-honma@nuhw.ac.jp
Sponsor or person
Institute
Niigata University of Health and Welfare
Institute
Department
Personal name
Funding Source
Organization
Niigata University of Health and Welfare
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Niigata University of Health and Welfare
Address
1398 Shimamicho, Kita-ku, Niigata City, Niigata Prefecture
Tel
0252574437
kenta-honma@nuhw.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 05 | Month | 27 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Preinitiation
Date of protocol fixation
| 2026 | Year | 05 | Month | 21 | Day |
Date of IRB
Anticipated trial start date
| 2026 | Year | 06 | Month | 01 | Day |
Last follow-up date
| 2026 | Year | 09 | Month | 30 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
Management information
Registered date
| 2026 | Year | 05 | Month | 27 | Day |
Last modified on
| 2026 | Year | 05 | Month | 27 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000070620
