UMIN-ICDS Clinical Trial
| Unique ID issued by UMIN | UMIN000061456 |
|---|---|
| Receipt number | R000070324 |
| Scientific Title | MRI-Based Visualization of Taste Perception Mechanisms |
| Date of disclosure of the study information | 2026/05/08 |
| Last modified on | 2026/05/06 00:47:49 |
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Basic information
Public title
MRI-Based Visualization of Taste Perception Mechanisms
Acronym
MRI-Based Visualization of Taste Perception Mechanisms
Scientific Title
MRI-Based Visualization of Taste Perception Mechanisms
Scientific Title:Acronym
MRI-Based Visualization of Taste Perception Mechanisms
Region
| Japan |
Condition
Condition
Healthy subjects
Classification by specialty
| Adult |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
This research seeks to decode the neural mechanisms underlying taste recognition through MRI-based detection of cortical activity triggered by complex flavors, including chocolate and potato chips. By integrating this with functional data on basic taste reception, we aim to visualize the neural circuitry of flavor perception-the interplay of taste and olfaction-and develop a comprehensive functional model.
Basic objectives2
Bio-availability
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
MRI images and regions of signal intensity changes during gustatory stimulation.
Key secondary outcomes
Base
Study type
Interventional
Study design
Basic design
Single arm
Randomization
Non-randomized
Randomization unit
Blinding
Open -no one is blinded
Control
Self control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
1
Purpose of intervention
Prevention
Type of intervention
| Other |
Interventions/Control_1
Olfactory and gustatory stimuli
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 20 | years-old | <= |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
(1) Male or female participants aged 20 years or older at the time of providing informed consent.
(2) Individuals with no gustatory dysfunction (taste disorders).
(3) Individuals who have provided voluntary written informed consent to participate in this study.
(4) Individuals capable of minimal communication necessary for the conduct of the study.
Key exclusion criteria
(1) Individuals with gustatory dysfunction (taste disorders).
(2) Individuals with oral mucosal diseases.
(3) Individuals with a severe gag reflex that makes dental treatment difficult.
(4) Individuals with a medical history of aspiration pneumonia.
(5) Individuals deemed ineligible based on the MRI pre-screening safety checklist.
(6) Other individuals judged by the Principal Investigator or Sub-investigator to be unsuitable for participation in the study.
Target sample size
30
Research contact person
Name of lead principal investigator
| 1st name | Hiroyasu |
| Middle name | |
| Last name | Kanetaka |
Organization
Tohoku University Graduate School of Dentistry
Division name
Division of Orthodontics and Dentofacial Orthopedics
Zip code
980-8575
Address
Seiryo-machi 4-1, Aoba-ku, Sendai
TEL
022-717-8374
hiroyasu.kanetaka.e6@tohoku.ac.jp
Public contact
Name of contact person
| 1st name | Eriya |
| Middle name | |
| Last name | Shimada |
Organization
Tohoku University Hospital
Division name
Department of Orthodontics
Zip code
980-8574
Address
Seiryo-machi 1-1, Aoba-ku, Sendai
TEL
022-717-8374
Homepage URL
eriya.shimada.c8@tohoku.ac.jp
Sponsor or person
Institute
Tohoku University
Institute
Department
Personal name
Funding Source
Organization
Meiji
Organization
Division
Category of Funding Organization
Profit organization
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Ethics Committee, Graduate School of Dentistry, Tohoku University
Address
Seiryo-machi 4-1, Aoba-ku, Sendai
Tel
022-717-8244
den-som@grp.tohoku.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 05 | Month | 08 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Preinitiation
Date of protocol fixation
| 2025 | Year | 10 | Month | 26 | Day |
Date of IRB
Anticipated trial start date
| 2025 | Year | 11 | Month | 30 | Day |
Last follow-up date
| 2028 | Year | 10 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
Management information
Registered date
| 2026 | Year | 05 | Month | 06 | Day |
Last modified on
| 2026 | Year | 05 | Month | 06 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000070324
