UMIN-ICDS Clinical Trial
| Unique ID issued by UMIN | UMIN000061369 |
|---|---|
| Receipt number | R000070217 |
| Scientific Title | Examining the neural basis of unconscious learning |
| Date of disclosure of the study information | 2026/04/24 |
| Last modified on | 2026/04/24 13:50:54 |
* This page includes information on clinical trials registered in UMIN clinical trial registed system.
* We don't aim to advertise certain products or treatments
Basic information
Public title
Examining the neural basis of unconscious learning
Acronym
ENS
Scientific Title
Examining the neural basis of unconscious learning
Scientific Title:Acronym
ENS
Region
| Japan |
Condition
Condition
healthy volunteers
Classification by specialty
| Adult |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
The aim is to compare and analyze changes in brain activity and neural networks under both conscious and unconscious learning conditions, and to clarify the neural basis for unconscious learning.
Basic objectives2
Others
Basic objectives -Others
We will use MRI to analyze changes in brain activity and neural networks under both conscious and unconscious learning conditions.
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
The data will consist of brain function and structure acquired by MRI. During MRI measurements for brain function measurement, a conditioning task will be performed, in which subjects will be presented with pairs of meaningless figures and positive or negative images. In some trials, the positive or negative images will be presented as subliminal stimuli and displayed for a presentation time below the visual recognition threshold (e.g., 16 ms).
Key secondary outcomes
Base
Study type
Interventional
Study design
Basic design
Single arm
Randomization
Non-randomized
Randomization unit
Blinding
Open -no one is blinded
Control
Uncontrolled
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
1
Purpose of intervention
Educational,Counseling,Training
Type of intervention
| Behavior,custom |
Interventions/Control_1
Meaningless figures are paired with positive or negative images to induce conditioning in the subjects.
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 18 | years-old | <= |
Age-upper limit
| 40 | years-old | >= |
Gender
Male and Female
Key inclusion criteria
Devices that meet MRI safety standards and do not fall under any exclusion criteria.
Key exclusion criteria
1 Pregnant women or women who may be pregnant
2 Individuals with higher brain dysfunction or mental illness
3 Individuals with visual impairments
4 Individuals with a history of cerebrovascular disease or circulatory disease
5 Individuals with metal, devices, or artificial objects implanted in their bodies
6 Individuals with tattoos
7 Individuals with claustrophobia
8 Individuals weighing 100 kg or more.
Target sample size
70
Research contact person
Name of lead principal investigator
| 1st name | Tomokazu |
| Middle name | |
| Last name | Tsurugizawa |
Organization
National Institute of Advanced Industrial Science and Technology (AIST)
Division name
Human Informatics and Interaction Research Institute
Zip code
3058568
Address
1-1-1, Higashi, Tsukuba-shi, Ibaraki
TEL
050-3522-4931
tsurugizawa@gmail.com
Public contact
Name of contact person
| 1st name | Tomokazu |
| Middle name | |
| Last name | Tsurugizawa |
Organization
National Institute of Advanced Industrial Science and Technology (AIST)
Division name
Human Informatics and Interaction Research Institute
Zip code
3058568
Address
1-1-1, Higashi, Tsukuba-shi, Ibaraki
TEL
050-3522-4931
Homepage URL
tsurugizawa@gmail.com
Sponsor or person
Institute
National Institute of Advanced Industrial Science and Technology (AIST)
Institute
Department
Personal name
Funding Source
Organization
National Institute of Advanced Industrial Science and Technology (AIST)
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
National Institute of Advanced Industrial Science and Technology (AIST)
Address
1-1-1, Higashi, Tsukuba-shi, Ibaraki
Tel
090-3522-4931
t-tsurugizawa@aist.go.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
--- Select One ---
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 04 | Month | 24 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Open public recruiting
Date of protocol fixation
| 2025 | Year | 10 | Month | 22 | Day |
Date of IRB
| 2025 | Year | 10 | Month | 22 | Day |
Anticipated trial start date
| 2025 | Year | 10 | Month | 22 | Day |
Last follow-up date
| 2030 | Year | 03 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
Management information
Registered date
| 2026 | Year | 04 | Month | 24 | Day |
Last modified on
| 2026 | Year | 04 | Month | 24 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000070217
