UMIN-ICDS Clinical Trial
| Unique ID issued by UMIN | UMIN000062474 |
|---|---|
| Receipt number | R000065294 |
| Scientific Title | Applications of CT in Forensic Science |
| Date of disclosure of the study information | 2026/08/05 |
| Last modified on | 2026/08/05 10:13:51 |
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Basic information
Public title
Applications of CT in Forensic Science
Acronym
Applications of CT in Forensic Science
Scientific Title
Applications of CT in Forensic Science
Scientific Title:Acronym
Applications of CT in Forensic Science
Region
| Japan |
Condition
Condition
forensic medicine
Classification by specialty
| Not applicable |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
The purpose of this study is to develop and evaluate a method for identifying unknown individuals using anatomical features obtained from computed tomography images. By comparing antemortem and postmortem CT images and analyzing individual variations in bone morphology and other anatomical structures, this study aims to establish objective imaging-based indicators that can be used for personal identification.
Basic objectives2
Efficacy
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
The primary outcome is the accuracy of distinguishing matched antemortem and postmortem CT images from unmatched images based on the three-dimensional spatial distribution of depressions on the inner table of the skull.
Identification performance will be evaluated using distance metrics between the extracted depression points, with the area under the receiver operating characteristic curve (AUC) as the primary measure.
Key secondary outcomes
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 40 | years-old | <= |
Age-upper limit
| 100 | years-old | >= |
Gender
Male and Female
Key inclusion criteria
Cases for which both antemortem and postmortem head CT images of the same individual are available.
Cases in which the CT scan range includes the cranial regions required for evaluating inner-table skull depressions and anatomical reference points.
Cases with CT image quality sufficient for extraction of three-dimensional coordinates and image analysis.
Cases in which the antemortem and postmortem CT images can be confirmed to belong to the same individual based on clinical or forensic information.
Key exclusion criteria
Cases with marked morphological alterations in the target cranial region caused by surgery, trauma, fracture, tumor, infection, or other pathological conditions.
Cases in which inner-table skull depressions or anatomical reference points cannot be adequately evaluated because of motion, metal, or other imaging artifacts.
Cases in which the required analysis cannot be performed because of insufficient scan coverage or missing image data.
Cases with severe postmortem changes, cranial deformation, or damage that preclude reliable comparison with the antemortem CT images.
Cases otherwise considered unsuitable for image analysis by the principal investigator.
Target sample size
50
Research contact person
Name of lead principal investigator
| 1st name | Kei |
| Middle name | |
| Last name | Okino |
Organization
Osaka Medical and Pharmaceutical University
Division name
Department of Diagnostic Radiology and Interventional Radiology/Department of Forensic Medicine
Zip code
5698686
Address
2-7 Daigaku-machi, Takatsuki, Osaka 569-8686, Japan
TEL
0726831221
kei.okino@ompu.ac.jp
Public contact
Name of contact person
| 1st name | Kei |
| Middle name | |
| Last name | Okino |
Organization
Osaka Medical and Pharmaceutical University
Division name
Department of Diagnostic Radiology and Interventional Radiology/Department of Forensic Medicine
Zip code
5698686
Address
2-7 Daigaku-machi, Takatsuki, Osaka 569-8686, Japan
TEL
09046456314
Homepage URL
kei.okino@ompu.ac.jp
Sponsor or person
Institute
Osaka Medical and Pharmaceutical University
Institute
Department
Personal name
Funding Source
Organization
none
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Osaka Medical and Pharmaceutical University
Address
2-7 Daigaku-machi, Takatsuki, Osaka 569-8686, Japan
Tel
0726831221
unknown
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 08 | Month | 05 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
50
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Completed
Date of protocol fixation
| 2025 | Year | 05 | Month | 19 | Day |
Date of IRB
| 2025 | Year | 05 | Month | 14 | Day |
Anticipated trial start date
| 2025 | Year | 05 | Month | 19 | Day |
Last follow-up date
| 2028 | Year | 03 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
none
Management information
Registered date
| 2026 | Year | 08 | Month | 05 | Day |
Last modified on
| 2026 | Year | 08 | Month | 05 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000065294
