Unique ID issued by UMIN | UMIN000055016 |
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Receipt number | R000062848 |
Scientific Title | Role of aldosterone in various target organ damage in patients with hypertensive emergency: A cross-sectional study |
Date of disclosure of the study information | 2024/07/19 |
Last modified on | 2024/07/19 09:09:49 |
Relationship between organ damage and aldosterone concentration in hypertensive emergency
Relationship between organ damage and aldosterone concentration in hypertensive emergency
Role of aldosterone in various target organ damage in patients with hypertensive emergency: A cross-sectional study
Role of aldosterone in organ damage in patients with hypertensive emergency
Japan |
hypertensive emergency
Nephrology |
Others
NO
This cross-sectional study was conducted to characterize the association between RAS and the organ damage in patients with hypertensive emergencies.
Others
This cross-sectional study was conducted to characterize the association between RAS and the organ damage in patients with hypertensive emergencies.
Hypertensive target organ damage was evaluated on admission, including severe kidney impairment (eGFR less than 30 mL/min/1.73 m2, SKI), severe retinopathy, concentric left ventricular hypertrophy (c-LVH), thrombotic microangiopathy (TMA), heart failure with reduced ejection fraction (HFrEF) and cerebrovascular disease. Then, whether each organ injury was associated with blood pressure or a plasma aldosterone concentration was analyzed.
Observational
18 | years-old | <= |
Not applicable |
Male and Female
During the period between April 2012 and August 2020, eighty-six patients visited the emergency department of Tokyo Bay Urayasu Ichikawa Medical Center, presenting with severe hypertension (systolicBP>180 mmHg and/or diastolic BP>120 mmHg) and the associated complications.
Among them, eighteen patients were transferred to other hospitals for further assessment and the treatment of severe hypertension. Of 68 patients admitted to our hospital, five patients died upon admission (i.e., before detailed evaluation); the causes of the death were brainstem hemorrhage (n=4) and aortic dissection (n=1). Ultimately, 63 patients were eligible for further evaluation.
63
1st name | Toshihiko |
Middle name | |
Last name | Suzuki |
Tokyo Bay Urayasu Ichikawa Medical Center
Department of Nephrology, Endocrinology & Diabetes
2790001
Urayasu city todaijima 3-4-32, Chiba
0473513101
toshi-s@xj9.so-net.ne.jp
1st name | Akihiro |
Middle name | |
Last name | Miyake |
Tokyo Bay Urayasu Ichikawa Medical Center
Department of Nephrology, Endocrinology & Diabetes
2790001
Urayasu city todaijima 3-4-32, Chiba
0473513101
akihiro.miyake19@gmail.com
Toshihiko Suzuki
Department of Nephrology, Endocrinology & Diabetes
Tokyo Bay Urayasu Ichikawa Medical Center
3-4-32 Todaijima
Urayasu, Chiba 279-0001
Japan
none.
Other
Tokyo Bay Urayasu Ichikawa Medical Center
Urayasu city todaijima 3-4-32, Chiba
0473513101
toshi-s@xj9.so-net.ne.jp
NO
2024 | Year | 07 | Month | 19 | Day |
Unpublished
63
Completed
2021 | Year | 09 | Month | 01 | Day |
2021 | Year | 11 | Month | 26 | Day |
2021 | Year | 09 | Month | 02 | Day |
2023 | Year | 12 | Month | 30 | Day |
none
2024 | Year | 07 | Month | 19 | Day |
2024 | Year | 07 | Month | 19 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000062848
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