Unique ID issued by UMIN | UMIN000054173 |
---|---|
Receipt number | R000061862 |
Scientific Title | Translational Research for Establishing Novel Prevention and nobel procedure in Cardiovascular Disease |
Date of disclosure of the study information | 2024/04/20 |
Last modified on | 2024/04/17 08:23:43 |
Translational Research for Establishing Novel Prevention and nobel procedure in Cardiovascular Disease
EHIME-CVS
Translational Research for Establishing Novel Prevention and nobel procedure in Cardiovascular Disease
EHIME-CVS
Japan |
Coronary artery lesions, valvular disease, aortic dissection (aortic wall), aortic aneurysm, aortic root dilatation, peripheral artery disease, Varicose veins
Vascular surgery | Cardiovascular surgery |
Others
YES
The pathogenesis and pathophysiology of many cardiovascular diseases are not well understood, and there is still no curative drug therapy. Therefore, it is necessary to analyze surgically harvested tissues in detail to elucidate the pathogenesis and understand the pathophysiology of diseases based on molecular, cellular, and tissue data. In this study, we aim to identify new drug targets for understanding the pathogenesis of cardiovascular diseases by analyzing surgical specimens obtained from surgical treatment of cardiovascular diseases in detail at the molecular, cellular, and tissue levels.
Others
Establishment of novel treatment methods
Pathological tests are performed on diseased and relatively unaffected tissues to identify therapeutic target factors by detailed analysis at the molecular, cellular, and tissue levels, and by comparative analysis of the composition of the two. Specifically, proteins and metabolic molecules are characterized using mass spectrometry, nucleic acids (called RNA) are characterized using sequencers, cells are characterized using temporary incubators, and tissues are characterized using special stains and immunohistochemical stains.
In addition, imaging studies are used to evaluate preoperative and postoperative disease
Blood tests, patient subjective assessment
Others,meta-analysis etc
1 | years-old | <= |
150 | years-old | > |
Male and Female
A person who performs surgical treatment in cardiovascular surgery
none
500
1st name | Hironori |
Middle name | |
Last name | Izutani |
Ehime University Graduate School of Medicine
Department of Cardiovascular and Thoracic Surgery
7910204
Shitsugawa, Toon-shi, EHIME, Japan
0899605331
shinkoge@m.ehime-u.ac.jp
1st name | Hironori |
Middle name | |
Last name | Izutani |
Ehime University Graduate School of Medicine
Ehime University Graduate School of Medicine
7910204
Shitsugawa, Toon-shi, EHIME, 791-0295, JAPAN
0899605331
shinkoge@m.ehime-u.ac.jp
Ehime University Graduate School of Medicine
Grants-in-Aid for Scientific Research
Japanese Governmental office
Japan
Ehime University Hospital
Shitsugawa, Toon-shi, EHIME, 791-0295, JAPAN
089-960-5331
shinkoge@m.ehime-u.ac.jp
NO
2024 | Year | 04 | Month | 20 | Day |
Unpublished
Open public recruiting
2019 | Year | 04 | Month | 01 | Day |
2023 | Year | 01 | Month | 24 | Day |
2019 | Year | 04 | Month | 01 | Day |
2030 | Year | 03 | Month | 31 | Day |
none
2024 | Year | 04 | Month | 17 | Day |
2024 | Year | 04 | Month | 17 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000061862