UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000061598 |
|---|---|
| Receipt number | R000070477 |
| Scientific Title | Comparison of the Immediate Effects of Muscle Energy Technique and Proprioceptive Neuromuscular Facilitation on Trigger Point Area, Fascia Thickness, Pain, and Range of Motion in Gastrocnemius Myofascial Pain Syndrome |
| Date of disclosure of the study information | 2026/05/18 |
| Last modified on | 2026/05/17 04:46:09 |
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Basic information
Public title
Comparison of the Immediate Effects of Muscle Energy Technique and Proprioceptive Neuromuscular Facilitation on Trigger Point Area and Fascia Thickness in Patients with Gastrocnemius Myofascial Pain Syndrome: A Randomized Controlled Trial Using Ultrasonography
Acronym
MET-PNF Gastrocnemius Trial
Scientific Title
Comparison of the Immediate Effects of Muscle Energy Technique and Proprioceptive Neuromuscular Facilitation on Trigger Point Area, Fascia Thickness, Pain, and Range of Motion in Gastrocnemius Myofascial Pain Syndrome
Scientific Title:Acronym
MET-PNF RCT
Region
| Asia(except Japan) |
Condition
Condition
Gastrocnemius Myofascial Pain Syndrome
Classification by specialty
| Orthopedics | Rehabilitation medicine | Adult |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
To compare the immediate effects of Muscle Energy Technique (MET) and Proprioceptive Neuromuscular Facilitation (PNF) on trigger point area, ultrasonographic fascia thickness, pain, and range of motion in Gastrocnemius Myofascial Pain Syndrome
Basic objectives2
Others
Basic objectives -Others
Rehabilitation intervention using Muscle Energy Technique and Proprioceptive Neuromuscular Facilitation assessed with ultrasonography
Trial characteristics_1
Confirmatory
Trial characteristics_2
Pragmatic
Developmental phase
Not applicable
Assessment
Primary outcomes
Changes in trigger point area and ultrasonographic fascia thickness immediately after intervention
Key secondary outcomes
Changes in pain intensity measured using the Visual Analog Scale (VAS) and ankle range of motion immediately after intervention
Base
Study type
Interventional
Study design
Basic design
Parallel
Randomization
Randomized
Randomization unit
Individual
Blinding
Double blind -all involved are blinded
Control
Active
Stratification
NO
Dynamic allocation
NO
Institution consideration
Institution is not considered as adjustment factor.
Blocking
NO
Concealment
Numbered container method
Intervention
No. of arms
2
Purpose of intervention
Treatment
Type of intervention
| Maneuver |
Interventions/Control_1
Muscle Energy Technique was applied to the gastrocnemius muscle using isometric contraction followed by stretching for one treatment session
Interventions/Control_2
Proprioceptive Neuromuscular Facilitation stretching was applied to the gastrocnemius muscle using the hold-relax technique for one treatment session
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 18 | years-old | <= |
Age-upper limit
| 25 | years-old | >= |
Gender
Male and Female
Key inclusion criteria
Participants diagnosed with Gastrocnemius Myofascial Pain Syndrome, aged 18 years or older, with active trigger points in the gastrocnemius muscle, and willing to participate in the study.
Key exclusion criteria
Participants with a history of lower limb fracture or surgery, neurological disorders, systemic musculoskeletal disease, skin lesions in the intervention area, or contraindications to manual therapy.
Target sample size
52
Research contact person
Name of lead principal investigator
| 1st name | Rezkiyanti |
| Middle name | Mutmainna |
| Last name | Abdullah |
Organization
Hasanuddin University
Division name
Biomedical Sciences Graduate Program
Zip code
90245
Address
Makassar, South Sulawesi, Indonesia
TEL
085241337056
kiikaayyee@gmail.com
Public contact
Name of contact person
| 1st name | Rezkiyanti |
| Middle name | Mutmainna |
| Last name | Abdullah |
Organization
Hasanuddin University
Division name
Biomedical Sciences Graduate Program
Zip code
90245
Address
Makassar, South Sulawesi, Indonesia
TEL
085241337056
Homepage URL
kiikaayyee@gmail.com
Sponsor or person
Institute
Others
Institute
Department
Personal name
Funding Source
Organization
Self-procurement
Organization
Division
Category of Funding Organization
Self funding
Nationality of Funding Organization
Indonesia
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Health Research Ethics Committee (KEPK) Faculty of Nursing Hasanuddin University
Address
Makassar, South Sulawesi, Indonesia
Tel
085241337056
kiikaayyee@gmail.com
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 05 | Month | 18 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Preinitiation
Date of protocol fixation
| 2026 | Year | 04 | Month | 11 | Day |
Date of IRB
| 2026 | Year | 04 | Month | 07 | Day |
Anticipated trial start date
| 2026 | Year | 05 | Month | 18 | Day |
Last follow-up date
| 2026 | Year | 05 | Month | 26 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
This study is a randomized controlled trial comparing the immediate effects of Muscle Energy Technique and Proprioceptive Neuromuscular Facilitation in patients with Gastrocnemius Myofascial Pain Syndrome using ultrasonographic assessment.
Management information
Registered date
| 2026 | Year | 05 | Month | 17 | Day |
Last modified on
| 2026 | Year | 05 | Month | 17 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070477
