UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000061515 |
|---|---|
| Receipt number | R000070376 |
| Scientific Title | The effect of differences in exercise timing based on individual circadian rhythms on glucose and lipid metabolism |
| Date of disclosure of the study information | 2026/05/12 |
| Last modified on | 2026/05/11 08:26:57 |
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Basic information
Public title
The effect of differences in exercise timing based on individual circadian rhythms on glucose and lipid metabolism
Acronym
The effect of differences in exercise timing based on individual circadian rhythms on metabolism responses
Scientific Title
The effect of differences in exercise timing based on individual circadian rhythms on glucose and lipid metabolism
Scientific Title:Acronym
The effect of differences in exercise timing based on individual circadian rhythms on metabolism responses
Region
| Japan |
Condition
Condition
None
Classification by specialty
| Adult |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
To investigate the effects of chronotype-matched and chronotype-mismatched exercise timing on glucose and lipid metabolism responses following acute exercise
Basic objectives2
Efficacy
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Free fatty acid
Key secondary outcomes
Glucose, triglycerides, total cholesterol, LDL cholesterol, HDL cholesterol, insulin, epinephrine, norepinephrine, cortisol, IL-6, core body temperature, continuous glucose monitoring
Base
Study type
Interventional
Study design
Basic design
Cross-over
Randomization
Randomized
Randomization unit
Individual
Blinding
Open -no one is blinded
Control
Active
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
2
Purpose of intervention
Educational,Counseling,Training
Type of intervention
| Other |
Interventions/Control_1
Perform moderate-intensity aerobic exercise in the morning
Interventions/Control_2
Perform moderate-intensity aerobic exercise in the evening
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 18 | years-old | <= |
Age-upper limit
| 34 | years-old | >= |
Gender
Male
Key inclusion criteria
Healthy adult males aged 18-34
Those who answered morning type (>=59) or evening type (<=41) on the Morningness-Eveningness Questionnaire
Key exclusion criteria
･Individuals with a medical diagnosis of diabetes or dyslipidemia
･Individuals using lipid/blood glucose lowering agents or metabolism related drugs and supplements
･Individuals taking antipsychotics, sleeping pills, or steroids that may affect circadian rhythms or clock gene fluctuations
･Individuals with sleep apnea syndrome
･Individuals with a pacemaker or metal implants in their body (excluding silver fillings)
･Individuals who will be working or traveling with time zones within 14 days prior to the pre-survey or during the study period
･Individuals with a body mass index (BMI) outside the range of 18.5-24.9 kg/m^2, or weighing less than 50.0 kg
･Individuals with high levels of physical activity (more than 150 minutes of moderate-to-high intensity physical activity per week: 600 METs or higher)
Target sample size
24
Research contact person
Name of lead principal investigator
| 1st name | Masaki |
| Middle name | |
| Last name | Takahashi |
Organization
Institute of Science Tokyo
Division name
Institute for Liberal Arts
Zip code
152-8550
Address
2-12-1 Ookayama, Meguro-ku, Tokyo
TEL
03-5734-2904
takahashi.m.1483@m.isct.ac.jp
Public contact
Name of contact person
| 1st name | Yuto |
| Middle name | |
| Last name | Watabe |
Organization
Institute of Science Tokyo
Division name
School of Environment and Society
Zip code
152-8550
Address
2-12-1 Ookayama, Meguro-ku, Tokyo
TEL
03-5734-2904
Homepage URL
watabe.y.08d5@m.isct.ac.jp
Sponsor or person
Institute
Institute of Science Tokyo
Institute
Department
Personal name
Funding Source
Organization
Institute of Science Tokyo
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Human Subjects for Science and Engineering Research Ethics Review Committee
Address
2-12-1 Ookayama, Meguro-ku, Tokyo 152-8550 Japan
Tel
03-5734-3808
human.ethics.comm-oo@adm.isct.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 05 | Month | 12 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Preinitiation
Date of protocol fixation
| 2026 | Year | 04 | Month | 27 | Day |
Date of IRB
Anticipated trial start date
| 2026 | Year | 06 | Month | 01 | Day |
Last follow-up date
| 2026 | Year | 12 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
Management information
Registered date
| 2026 | Year | 05 | Month | 11 | Day |
Last modified on
| 2026 | Year | 05 | Month | 11 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070376
