UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000061117 |
|---|---|
| Receipt number | R000069939 |
| Scientific Title | Impact of Training History on Skeletal Muscle Adaptations to Resistance Training, Detraining, and Retraining |
| Date of disclosure of the study information | 2026/04/14 |
| Last modified on | 2026/04/13 11:47:26 |
* This page includes information on clinical trials registered in UMIN clinical trial registed system.
* We don't aim to advertise certain products or treatments
Basic information
Public title
Resistance Training Study
Acronym
RT Study
Scientific Title
Impact of Training History on Skeletal Muscle Adaptations to Resistance Training, Detraining, and Retraining
Scientific Title:Acronym
RT-DT-reRT Study
Region
| Japan |
Condition
Condition
Not applicable: Healthy men volunteers
Classification by specialty
| Adult |
Classification by malignancy
Others
Genomic information
YES
Objectives
Narrative objectives1
To determine how prior training status influences skeletal muscle adaptations to resistance training, as well as responses during detraining and retraining.
Basic objectives2
Others
Basic objectives -Others
Comparison of skeletal muscle adaptations to resistance training, detraining, and retraining according to prior training status.
Trial characteristics_1
Confirmatory
Trial characteristics_2
Explanatory
Developmental phase
Not applicable
Assessment
Primary outcomes
Changes in human muscle mass following 10 weeks of resistance training, 12 weeks of detraining, and 10 weeks of retraining.
Key secondary outcomes
Changes in skeletal muscle and circulating protein levels, as well as gene expression, following 10 weeks of resistance training, 12 weeks of detraining, and 10 weeks of retraining.
Base
Study type
Interventional
Study design
Basic design
Single arm
Randomization
Non-randomized
Randomization unit
Blinding
Open -no one is blinded
Control
Self control
Stratification
NO
Dynamic allocation
NO
Institution consideration
Institution is not considered as adjustment factor.
Blocking
NO
Concealment
No need to know
Intervention
No. of arms
1
Purpose of intervention
Educational,Counseling,Training
Type of intervention
| Behavior,custom |
Interventions/Control_1
All participants underwent a sequential protocol consisting of 10 weeks of resistance training, followed by 12 weeks of detraining and 10 weeks of retraining.
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 18 | years-old | <= |
Age-upper limit
| 30 | years-old | >= |
Gender
Male
Key inclusion criteria
Healthy men aged between 18 and 30.
Participants who have been assessed by the principal investigator or a co-investigator and found to be in good health.
Participants who have received a full explanation of the studys objectives and methods and have provided written consent.
Key exclusion criteria
Those who have orthopedic conditions affecting the upper or lower extremities.
Those who have known allergies to any food components included in the provided meals.
Those who have confirmed or suspected hepatitis B or C infection.
Those who have a history of cardiovascular disease, including heart disease or hypertension.
Those who are deemed unsuitable for participation by the principal investigator.
Target sample size
90
Research contact person
Name of lead principal investigator
| 1st name | Satoshi |
| Middle name | |
| Last name | Fujita |
Organization
Ritsumeikan University
Division name
Faculty of Sport and Health Science
Zip code
525-8577
Address
1-1-1, Nojihigashi, Kusatsu, Shiga
TEL
077-561-5229
safujita@fc.ritsumei.ac.jp
Public contact
Name of contact person
| 1st name | Satoshi |
| Middle name | |
| Last name | Fujita |
Organization
Ritsumeikan University
Division name
Faculty of Sport and Health Science
Zip code
525-8577
Address
1-1-1, Nojihigashi, Kusatsu, Shiga
TEL
077-561-5229
Homepage URL
safujita@fc.ritsumei.ac.jp
Sponsor or person
Institute
Ritsumeikan University
Institute
Department
Personal name
Funding Source
Organization
Japan Agency for Medical Research and Development
Organization
Division
Category of Funding Organization
Japanese Governmental office
Nationality of Funding Organization
Japan
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Ritsumeikan University
Address
1-1-1, Nojihigashi, Kusatsu, Shiga
Tel
077-599-4175
b-rinripst.ritsumei.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
立命館大学（滋賀県）
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 04 | Month | 14 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Open public recruiting
Date of protocol fixation
| 2026 | Year | 01 | Month | 15 | Day |
Date of IRB
| 2026 | Year | 03 | Month | 17 | Day |
Anticipated trial start date
| 2026 | Year | 03 | Month | 30 | Day |
Last follow-up date
| 2029 | Year | 02 | Month | 28 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
Management information
Registered date
| 2026 | Year | 03 | Month | 31 | Day |
Last modified on
| 2026 | Year | 04 | Month | 13 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069939
