UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000061080 |
|---|---|
| Receipt number | R000069890 |
| Scientific Title | Effects of collagen tripeptide supplementation combined with resistance training on morphological and functional properties of the Achilles tendon and triceps surae |
| Date of disclosure of the study information | 2026/03/30 |
| Last modified on | 2026/03/30 11:43:25 |
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Basic information
Public title
Effects of collagen tripeptide supplementation combined with resistance training on Achilles tendon and calf muscle properties
Acronym
Collagen and Training Study (Achilles Tendon and Calf)
Scientific Title
Effects of collagen tripeptide supplementation combined with resistance training on morphological and functional properties of the Achilles tendon and triceps surae
Scientific Title:Acronym
COL-RT Trial
Region
| Japan |
Condition
Condition
Achilles tendinopathy
Classification by specialty
| Orthopedics |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
To investigate the effects of collagen tripeptide supplementation combined with resistance training on the morphological and functional properties of the Achilles tendon and triceps surae.
Basic objectives2
Efficacy
Basic objectives -Others
Trial characteristics_1
Exploratory
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Tendon stiffness, tendon volume, tendon cross-sectional area, muscle volume, and muscle cross-sectional area
Key secondary outcomes
Base
Study type
Interventional
Study design
Basic design
Parallel
Randomization
Non-randomized
Randomization unit
Blinding
Double blind -all involved are blinded
Control
Placebo
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
2
Purpose of intervention
Educational,Counseling,Training
Type of intervention
| Food |
Interventions/Control_1
Collagen tripeptide supplementation
Participants will ingest collagen tripeptide (product name: HACP-BV50) orally once daily at a dose of 2 g (one packet) for a period of 14 weeks.
Each packet (2 g) contains 7 kcal of energy, 1.8 g of protein, 0 g of fat, 0 g of carbohydrates, and 0.03 g of salt equivalent. The total collagen content is 1800 mg, including 810 mg of tripeptides. The product is manufactured in Japan.
Interventions/Control_2
maltodextrin supplementation
Participants will ingest maltodextrin orally once daily at a dose of 2 g (one packet) for a period of 14 weeks.
This intervention will be administered as a placebo and will be matched to the collagen tripeptide supplementation in terms of administration method and frequency.
Each packet (2 g) contains approximately 8 kcal of energy, 0 g of protein, 0 g of fat, approximately 2 g of carbohydrates, and 0 g of salt equivalent.
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 18 | years-old | <= |
Age-upper limit
| 25 | years-old | >= |
Gender
Male
Key inclusion criteria
Healthy young males with no regular exercise habits, a body mass index (BMI) between 18.5 and 25.0
Key exclusion criteria
history of lower extremity musculoskeletal injuries
Target sample size
24
Research contact person
Name of lead principal investigator
| 1st name | takashi |
| Middle name | |
| Last name | okada |
Organization
Nippon Sport Science University
Division name
School of Sport and Health Science
Zip code
1588508
Address
7-1-1 Fukasawa, Setagaya-ku, Tokyo 158-8508, Japan
TEL
03-5706-1024
t-okada@nittai.ac.jp
Public contact
Name of contact person
| 1st name | shogo |
| Middle name | |
| Last name | okamura |
Organization
Nippon Sport Science University
Division name
graduate school
Zip code
1588508
Address
7-1-1 Fukasawa, Setagaya-ku, Tokyo 158-8508, Japan
TEL
08027199390
Homepage URL
25sda06@nittai.ac.jp
Sponsor or person
Institute
Nippon Sport Science University
Institute
Department
Personal name
Funding Source
Organization
Jellice Co., Ltd.
Organization
Division
Category of Funding Organization
Profit organization
Nationality of Funding Organization
Other related organizations
Co-sponsor
Jellice Co., Ltd.; Integrate Co., Ltd.
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Nippon Sport Science University
Address
7-1-1 Fukasawa, Setagaya-ku, Tokyo 158-8508, Japan
Tel
03-5706-0931
rinri-shinsa@nittai.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
日本体育大学世田谷キャンパス
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 03 | Month | 30 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
21
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
No longer recruiting
Date of protocol fixation
| 2025 | Year | 01 | Month | 01 | Day |
Date of IRB
| 2023 | Year | 10 | Month | 11 | Day |
Anticipated trial start date
| 2025 | Year | 01 | Month | 01 | Day |
Last follow-up date
| 2026 | Year | 04 | Month | 30 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
Management information
Registered date
| 2026 | Year | 03 | Month | 27 | Day |
Last modified on
| 2026 | Year | 03 | Month | 30 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069890
