UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000060931 |
|---|---|
| Receipt number | R000069729 |
| Scientific Title | Exploratory Investigation of Senescence-Associated Glycoprotein (SAGP) Expression in Idiopathic Pulmonary Fibrosis: A Retrospective Observational Study Using Archived Lung Tissue Specimens |
| Date of disclosure of the study information | 2026/04/01 |
| Last modified on | 2026/03/13 17:55:38 |
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Basic information
Public title
A Retrospective Observational Study of Senescence-Associated Glycoprotein (SAGP) Expression in Idiopathic Pulmonary Fibrosis Using Archived Lung Tissue Samples
Acronym
IPF-SAGP Retrospective Study
Scientific Title
Exploratory Investigation of Senescence-Associated Glycoprotein (SAGP) Expression in Idiopathic Pulmonary Fibrosis: A Retrospective Observational Study Using Archived Lung Tissue Specimens
Scientific Title:Acronym
SAGP-IPF Retrospective Study
Region
| Japan |
Condition
Condition
Idiopathic pulmonary fibrosis
Classification by specialty
| Medicine in general | Cardiology | Pneumology |
| Geriatrics |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
The objective of this study is to determine the presence of senescence-associated glycoprotein (SAGP) expression in archived lung tissue specimens obtained from patients diagnosed with idiopathic pulmonary fibrosis (IPF).
Basic objectives2
Bio-availability
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Presence or absence of senescence-associated glycoprotein (SAGP) expression in archived lung tissue specimens
Key secondary outcomes
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 16 | years-old | <= |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
1. Patients diagnosed with idiopathic pulmonary fibrosis at Juntendo University Hospital between April 1, 2009 and December 31, 2025, for whom archived lung tissue specimens are available
2. Patients whose archived lung tissue specimens and clinical information are available for research use
Key exclusion criteria
1.Patients judged by the principal investigator to be inappropriate for inclusion in the study
2.Patients who have expressed refusal to participate in the study (opt-out)
Target sample size
10
Research contact person
Name of lead principal investigator
| 1st name | Tohru |
| Middle name | |
| Last name | Minamino |
Organization
Juntendo University Hospital
Division name
Department of Cardiovascular Biology and Medicine
Zip code
113-8431
Address
3-1-3 Hongo, Bunkyo-ku, Tokyo
TEL
03-3813-3111
t.minamino@juntendo.ac.jp
Public contact
Name of contact person
| 1st name | Yusuke |
| Middle name | |
| Last name | Joki |
Organization
Juntendo University Hospital
Division name
Department of Cardiovascular Biology and Medicine
Zip code
113-8431
Address
3-1-3 Hongo, Bunkyo-ku, Tokyo
TEL
0338133111
Homepage URL
yjyouki@juntendo.ac.jp
Sponsor or person
Institute
Juntendo University Hospital
Institute
Department
Personal name
Funding Source
Organization
Departmental research funding, Juntendo University Hospital
Organization
Division
Category of Funding Organization
Self funding
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Medical Research Ethics Committee, Juntendo University
Address
3-1-3 Hongo, Bunkyo-ku, Tokyo
Tel
03-3814-5672
hongo-rinri@juntendo.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 04 | Month | 01 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Preinitiation
Date of protocol fixation
| 2026 | Year | 03 | Month | 10 | Day |
Date of IRB
Anticipated trial start date
| 2026 | Year | 04 | Month | 01 | Day |
Last follow-up date
| 2030 | Year | 03 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
This is a single-center retrospective observational study. Patients diagnosed with idiopathic pulmonary fibrosis between April 1, 2009 and December 31, 2025, for whom archived lung tissue specimens are available, will be included. No additional interventions or procedures will be performed. The study aims to explore the presence or absence of senescence-associated glycoprotein (SAGP) expression in archived lung tissue specimens.
Management information
Registered date
| 2026 | Year | 03 | Month | 13 | Day |
Last modified on
| 2026 | Year | 03 | Month | 13 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069729
