UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000060880 |
|---|---|
| Receipt number | R000069666 |
| Scientific Title | A study on the characteristics of taste disorders induced by selective P2X3 receptor antagonists in patients with asthmatic refractory cough |
| Date of disclosure of the study information | 2026/03/10 |
| Last modified on | 2026/03/09 22:02:52 |
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Basic information
Public title
A study on the characteristics of taste disorders induced by selective P2X3 receptor antagonists in patients with asthmatic refractory cough
Acronym
taste disorders caused by P2X3 receptor antagonists in asthmatic refractory cough
Scientific Title
A study on the characteristics of taste disorders induced by selective P2X3 receptor antagonists in patients with asthmatic refractory cough
Scientific Title:Acronym
taste disorders caused by P2X3 receptor antagonists in asthmatic refractory cough
Region
| Japan |
Condition
Condition
asthma
Classification by specialty
| Pneumology |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
To clarify the qualitative characteristics of taste disorders following gefapixant administration in patients with asthmatic refractory chronic cough
Basic objectives2
Others
Basic objectives -Others
side effects
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Changes in the four basic taste modalities on the visual analog scale from baseline to 6 months after treatment
Key secondary outcomes
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 18 | years-old | <= |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
1.Adult patients diagnosed with asthmatic refractory chronic cough between January 2021 and December 2025.
2.Patients who received P2X3 receptor antagonists for 6 months.
3.Patients who completed both cough- and taste-related questionnaires as well as electrogustometry tests.
Key exclusion criteria
1. Patients deemed ineligible for this study by the investigators or research staff.
Target sample size
10
Research contact person
Name of lead principal investigator
| 1st name | Tomoko |
| Middle name | |
| Last name | Tajiri |
Organization
Nagoya City University Graduate School of Medicine
Division name
Department of Respiratory Medicine, Allergy and Clinical Immunology
Zip code
4678601
Address
1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya
TEL
+81528538216
tomokot@med.nagoya-cu.ac.jp
Public contact
Name of contact person
| 1st name | Tomoko |
| Middle name | |
| Last name | Tajiri |
Organization
Nagoya City University Graduate School of Medical Sciences
Division name
Department of Respiratory Medicine, Allergy and Clinical Immunology
Zip code
4678206
Address
1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya
TEL
81528538216
Homepage URL
tomokot@med.nagoya-cu.ac.jp
Sponsor or person
Institute
Nagoya City University
Institute
Department
Personal name
Funding Source
Organization
Nagoya City University
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Nagoya City University medical research ethics committee
Address
1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya
Tel
81528515511
clinical_research@med.nagoya-cu.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 03 | Month | 10 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Open public recruiting
Date of protocol fixation
| 2026 | Year | 02 | Month | 22 | Day |
Date of IRB
| 2026 | Year | 03 | Month | 02 | Day |
Anticipated trial start date
| 2026 | Year | 03 | Month | 02 | Day |
Last follow-up date
| 2026 | Year | 12 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
None
Management information
Registered date
| 2026 | Year | 03 | Month | 09 | Day |
Last modified on
| 2026 | Year | 03 | Month | 09 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069666
