UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000060080 |
|---|---|
| Receipt number | R000068712 |
| Scientific Title | Prophylactic use of constipation drugs for prevention of opioidinduced constipation in patients with opioid starting: a systematic review and meta-analysis |
| Date of disclosure of the study information | 2025/12/14 |
| Last modified on | 2025/12/14 16:35:24 |
* This page includes information on clinical trials registered in UMIN clinical trial registed system.
* We don't aim to advertise certain products or treatments
Basic information
Public title
Prophylactic use of constipation drugs for prevention of opioidinduced
constipation in patients with opioid starting: a systematic
review and meta-analysis
Acronym
Prophylactic use of constipation drugs for prevention of opioidinduced
constipation in patients with opioid starting: a systematic
review and meta-analysis
Scientific Title
Prophylactic use of constipation drugs for prevention of opioidinduced
constipation in patients with opioid starting: a systematic
review and meta-analysis
Scientific Title:Acronym
Prophylactic use of constipation drugs for prevention of opioidinduced
constipation in patients with opioid starting: a systematic
review and meta-analysis
Region
| Japan |
Condition
Condition
Patients with opioid starting
Classification by specialty
| Medicine in general | Gastroenterology |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
We conducted a systematic review and meta-analysis on the prophylactic use of naldemedine for the prevention of opioid-induced constipation in patients initiating opioid therapy.
Basic objectives2
Others
Basic objectives -Others
none
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
a systematic review, meta-analysis
Key secondary outcomes
Base
Study type
Others,meta-analysis etc
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 18 | years-old | <= |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
Patients with opioid starting
Key exclusion criteria
none
Target sample size
Research contact person
Name of lead principal investigator
| 1st name | Takaomi |
| Middle name | |
| Last name | Kessoku |
Organization
IUHW Narita hospital
Division name
Palliative medicine and Gastroenterology
Zip code
286-8520
Address
852, Hatakeda, Narita, Chiba, Japan
TEL
0476355600
takaomi0027@gmail.com
Public contact
Name of contact person
| 1st name | Takaomi |
| Middle name | |
| Last name | Kessoku |
Organization
International university of health and welfare Narita hospital
Division name
Palliative medicine and Gastroenterology
Zip code
286-8520
Address
852, Hatakeda, Narita, Chiba, Japan
TEL
0476355600
Homepage URL
takaomi0027@gmail.com
Sponsor or person
Institute
IUHW
Institute
Department
Personal name
Funding Source
Organization
Self
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
NA
Address
NA
Tel
NA
NA
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2025 | Year | 12 | Month | 14 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Preinitiation
Date of protocol fixation
| 2025 | Year | 12 | Month | 14 | Day |
Date of IRB
Anticipated trial start date
| 2026 | Year | 01 | Month | 01 | Day |
Last follow-up date
| 2026 | Year | 03 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
syastematic review, metaanalysis
P: Patients with opioid starting
I: Constipation drugs (based on drugs)
C: no constipation drugs
O: Constipation preventon
Management information
Registered date
| 2025 | Year | 12 | Month | 14 | Day |
Last modified on
| 2025 | Year | 12 | Month | 14 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068712
