UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000059679 |
|---|---|
| Receipt number | R000068265 |
| Scientific Title | Fatty Acids and their Potential Neuroprotective Function in Postoperative Delirium: A Scoping Review |
| Date of disclosure of the study information | 2025/11/07 |
| Last modified on | 2026/02/02 17:54:43 |
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Basic information
Public title
Fatty Acids and their Potential Neuroprotective Function in Postoperative Delirium: A Scoping Review
Acronym
POD-SCOPE
Scientific Title
Fatty Acids and their Potential Neuroprotective Function in Postoperative Delirium: A Scoping Review
Scientific Title:Acronym
POD-SCOPE
Region
| Japan |
Condition
Condition
Postoperative Delirium
Classification by specialty
| Neurology | Clinical immunology | Surgery in general |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
To map and synthesize the current evidence on the relationship between fatty acids (including circulating fatty acid profiles and fatty acid based interventions) and postoperative delirium, based on both clinical and animal studies.
Basic objectives2
Others
Basic objectives -Others
To identify and summarize proposed biological mechanisms by which fatty acids may influence the pathogenesis of postoperative delirium, with particular attention to findings from animal models.
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
An evidence map describing studies that examine the relationship between fatty acids and postoperative delirium or delirium-like cognitive impairment.
Key secondary outcomes
Base
Study type
Others,meta-analysis etc
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 65 | years-old | <= |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
Data of Publishment: 1980-2025
Article Type: Reviews; Trials (clinical + RCT); Meta Analyses; Observational studies; Animal Studies
Concept of Paper: The function and effects of fatty acids on postoperative acute behavioural or cognitive changes
Population (if required): 65<= years old; Surgery patients
Data type (if required): Quantitative
Language: English Only
Publication Type: Peer-reviewed journal articles only
Key exclusion criteria
Studies that focus on chronic neurological conditions rather than acute postoperative behavioral or cognitive changes.
Studies that are irrelevant to the concept of fatty acids functions or effects on postoperative acute behavioral or cognitive changes.
Studies that involve direct surgical procedures on the central nervous system.
Animal studies that include only young animals (mice < 16 months; rats < 18 months).
Review articles that do not contain original data.
Target sample size
Research contact person
Name of lead principal investigator
| 1st name | Louis |
| Middle name | Vincent |
| Last name | Wotton |
Organization
National Cancer Center Hospital, Tsukiji
Division name
Department of Psycho-oncology
Zip code
104-0045
Address
5-1-1 Tsukiji, Chuo-ku, Tokyo, Japan
TEL
9084248863
rutton@ncc.go.jp
Public contact
Name of contact person
| 1st name | Louis |
| Middle name | Vincent |
| Last name | Wotton |
Organization
National Cancer Center Hospital Tokyo
Division name
Department of Pyscho-oncology
Zip code
104-0045
Address
5-1-1, Tsukiji, Chuo-ku, Tokyo, Japan
TEL
9084248863
Homepage URL
rutton@ncc.go.jp
Sponsor or person
Institute
National Cancer Center Hospital, Tsukiji
Institute
Department
Personal name
Ryoichi Sadahiro
Funding Source
Organization
National Cancer Center Hospital, Tsukiji
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
N/A for a scoping review
Address
N/A
Tel
N/A
N/A
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2025 | Year | 11 | Month | 07 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Preinitiation
Date of protocol fixation
| 2025 | Year | 11 | Month | 06 | Day |
Date of IRB
Anticipated trial start date
| 2025 | Year | 11 | Month | 07 | Day |
Last follow-up date
| 2025 | Year | 11 | Month | 21 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
No recruiting required for this scoping review. Start date and final follow up date reflect the estimated start and end dates for the production of this paper.
Management information
Registered date
| 2025 | Year | 11 | Month | 07 | Day |
Last modified on
| 2026 | Year | 02 | Month | 02 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068265
