UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000058760 |
|---|---|
| Receipt number | R000067182 |
| Scientific Title | Efficacy and safety of vasopressor use in adult patients with traumatic hemorrhagic shock: systematic review |
| Date of disclosure of the study information | 2025/08/30 |
| Last modified on | 2025/08/11 16:12:24 |
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Basic information
Public title
Efficacy and safety of vasopressor use in adult patients with traumatic hemorrhagic shock: systematic review
Acronym
Efficacy and safety of vasopressor use in adult patients with traumatic hemorrhagic shock: systematic review
Scientific Title
Efficacy and safety of vasopressor use in adult patients with traumatic hemorrhagic shock: systematic review
Scientific Title:Acronym
Efficacy and safety of vasopressor use in adult patients with traumatic hemorrhagic shock: systematic review
Region
| Japan |
Condition
Condition
Adult patients with traumatic hemorrhagic shock
Classification by specialty
| Emergency medicine |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
This systematic review aims to evaluate the efficacy and safety of vasopressor administration in adult patients with traumatic hemorrhagic shock.
Basic objectives2
Others
Basic objectives -Others
NA
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Primary outcomes
1. All-cause mortality at the longest follow-up available.
2. Health-related quality of life (HRQoL), when reported.
3. Short-term mortality, defined as death within 24 hours, 7 days, or 30 days from injury or randomization.
Key secondary outcomes
Secondary outcomes
4. Length of ICU stay
5. Length of hospital stay
6. Occurrence of organ dysfunction, including multiple organ dysfunction syndrome (MODS) according to definitions used in the included studies.
7. Adverse events related to vasopressor use, such as arrhythmia, myocardial infarction, digital or mesenteric ischemia, acute kidney injury.
Base
Study type
Others,meta-analysis etc
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| Not applicable |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
See the attached protocol
Key exclusion criteria
See the attached protocol
Target sample size
Research contact person
Name of lead principal investigator
| 1st name | Yohei |
| Middle name | |
| Last name | Okada |
Organization
Kyoto University
Division name
Dept of Preventive Services
Zip code
See the attached protocol
Address
See the attached protocol
TEL
+819043018831
yokada-kyf@umin.ac.jp
Public contact
Name of contact person
| 1st name | Yohei |
| Middle name | |
| Last name | Okaad |
Organization
See the attached protocol
Division name
See the attached protocol
Zip code
See the attached protocol
Address
See the attached protocol
TEL
+819043018831
Homepage URL
yokada-kyf@umin.ac.jp
Sponsor or person
Institute
Kyoto University
Institute
Department
Personal name
Funding Source
Organization
Japanese Association of Trauma Surgery
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
NA
Address
NA
Tel
NA
NA
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2025 | Year | 08 | Month | 30 | Day |
Related information
URL releasing protocol
MEDRXIV/2025/333169
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Preinitiation
Date of protocol fixation
| 2025 | Year | 07 | Month | 15 | Day |
Date of IRB
Anticipated trial start date
| 2025 | Year | 08 | Month | 01 | Day |
Last follow-up date
| 2026 | Year | 01 | Month | 01 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
See the attached protocol in English
MEDRXIV/2025/333169
TITLE: Efficacy and safety of vasopressor use in adult patients with traumatic hemorrhagic shock: systematic review
Management information
Registered date
| 2025 | Year | 08 | Month | 11 | Day |
Last modified on
| 2025 | Year | 08 | Month | 11 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000067182
