UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000058194 |
|---|---|
| Receipt number | R000066529 |
| Scientific Title | Research on Stroke Using Primary Cultured Cells |
| Date of disclosure of the study information | 2025/06/18 |
| Last modified on | 2025/06/16 17:27:47 |
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Basic information
Public title
Study on Cerebral Circulatory and Metabolic Mechanisms Using Human Samples in Cerebrovascular Disorders
Acronym
Research on Stroke Using Primary Cultured Cells
Scientific Title
Research on Stroke Using Primary Cultured Cells
Scientific Title:Acronym
Research on Stroke Using Primary Cultured Cells
Region
| Japan |
Condition
Condition
Cerebrovascular Disease
Classification by specialty
| Neurology | Neurosurgery |
Classification by malignancy
Others
Genomic information
YES
Objectives
Narrative objectives1
To elucidate the causes of stroke and improve therapeutic techniques, we utilize in vitro analyses of blood, urine, and cerebrospinal fluid samples collected during routine clinical care in the stroke department, as well as tissue specimens excised or collected for therapeutic purposes or otherwise destined for disposal. In recent years, novel genes and hormones associated with cerebrovascular abnormalities have been reported. Through in vitro analyses (including those using primary cells) it may become possible to identify new pathological mechanisms and elucidate cerebral circulatory and metabolic responses at the cellular level during cerebral ischemia and hemorrhage.
Basic objectives2
Others
Basic objectives -Others
Observational Study
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Analyze the characteristics of the collected cells
Key secondary outcomes
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| Not applicable |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
Individuals who undergo clinical care in the Stroke Department of the University of Tsukuba Hospital and from whom some form of tissue sampling is performed
Key exclusion criteria
Individuals from whom consent for the use of their information or biological samples in this study could not be obtained, either from the individual themselves or from a legally authorized representative such as a family member.
Individuals deemed unsuitable for participation in this study by the principal investigator or co-investigators.
Target sample size
500
Research contact person
Name of lead principal investigator
| 1st name | Aiki |
| Middle name | |
| Last name | Marushima |
Organization
University of Tsukuba Hospital
Division name
Department of Stroke and Cerebrovascular Disease
Zip code
305-8575
Address
2-1-1, Amakubo, Tsukuba, Ibaraki, Japan
TEL
0298532951
aiki.marushima@md.tsukuba.ac.jp
Public contact
Name of contact person
| 1st name | Sho |
| Middle name | |
| Last name | Okune |
Organization
University of Tsukuba Hospital
Division name
Department of stroke and cerebrovascular disease
Zip code
305-8575
Address
2-1-1, Amakubo, Tsukuba, Ibaraki, Japan
TEL
0298532951
Homepage URL
sho.oku27@md.stukuba.ac.jp
Sponsor or person
Institute
University of Tsukuba
Institute
Department
Personal name
Sho Okune
Funding Source
Organization
The Japan Society for the Promotion of Science
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Tsukuba Clinical Research and Development Organization
Address
2-1-1, Amakubo, Tsukuba, Ibaraki, Japan
Tel
0298533914
rinshokenkyu@un.tsukuba.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Ibaraki
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2025 | Year | 06 | Month | 18 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Preinitiation
Date of protocol fixation
| 2025 | Year | 06 | Month | 18 | Day |
Date of IRB
Anticipated trial start date
| 2025 | Year | 06 | Month | 18 | Day |
Last follow-up date
| 2030 | Year | 03 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
none
Management information
Registered date
| 2025 | Year | 06 | Month | 16 | Day |
Last modified on
| 2025 | Year | 06 | Month | 16 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000066529
