UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000057920 |
|---|---|
| Receipt number | R000066208 |
| Scientific Title | Effect of eating disorders on salivary biomarkers: A systematic review and meta-analysis |
| Date of disclosure of the study information | 2025/05/21 |
| Last modified on | 2026/02/24 12:03:59 |
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Basic information
Public title
Effect of eating disorders on salivary biomarkers: A systematic review and meta-analysis
Acronym
Effect of eating disorders on salivary biomarkers: A systematic review and meta-analysis
Scientific Title
Effect of eating disorders on salivary biomarkers: A systematic review and meta-analysis
Scientific Title:Acronym
Effect of eating disorders on salivary biomarkers: A systematic review and meta-analysis
Region
| Japan |
Condition
Condition
Eating disorders
Classification by specialty
| Psychiatry |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
Objective: To conduct a systematic review and meta-analysis of the existing literature comparing on salivary cortisol and amylase levels in patients with eating disorders compared with those in healthy controls.
Basic objectives2
Efficacy
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Salivary cortisol and amylase levels
Key secondary outcomes
Base
Study type
Others,meta-analysis etc
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| Not applicable |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
1) Population: all ages and gender of adults and children
2) Exposure: patients with eating disorders
3) Comparison: Healthy control group with normal weight individuals
4) Outcomes: Salivary cortisol and/or amylase Levels
5) Study design: Observational studies, including cross-sectional, cohort, case-control, and interventional studies.
Key exclusion criteria
1) Duplicated publications
2) Animal subjects
3) Review article, meta-analysis, and conference abstracts
4) Unavailability of the full text
5) Non-English publications
Target sample size
Research contact person
Name of lead principal investigator
| 1st name | Takahiro |
| Middle name | |
| Last name | Seura |
Organization
Hokkaido University of Education
Division name
Asahikawa Campus
Zip code
070-8621
Address
9 Hokumon-cho, Asahikawa, Hokkaido
TEL
0166591361
seura.takahiro@a.hokkyodai.ac.jp
Public contact
Name of contact person
| 1st name | Takahiro |
| Middle name | |
| Last name | Seura |
Organization
Hokkaido University of Education
Division name
Asahikawa Campus
Zip code
070-8621
Address
9 Hokumon-cho, Asahikawa, Hokkaido
TEL
0166591361
Homepage URL
seura.takahiro@a.hokkyodai.ac.jp
Sponsor or person
Institute
Hokkaido University of Education
Institute
Department
Personal name
Takahiro Seura
Funding Source
Organization
Hokkaido University of Education
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Hokkaido University of Education
Address
9 Hokumon-cho, Asahikawa, Hokkaido
Tel
0166591361
seura.takahiro@a.hokkyodai.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
北海道
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2025 | Year | 05 | Month | 21 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Completed
Date of protocol fixation
| 2024 | Year | 10 | Month | 01 | Day |
Date of IRB
| 2024 | Year | 12 | Month | 01 | Day |
Anticipated trial start date
| 2024 | Year | 12 | Month | 01 | Day |
Last follow-up date
| 2025 | Year | 12 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
A systematic literature search was conducted across three electronic databases: PubMed, ScienceDirect, and Scopus. The search strategy incorporated Medical Subject Headings (MeSH) and relevant keywords related to eating disorders, salivary biomarkers, cortisol, and amylase. Specifically, terms included "eating disorders," "anorexia nervosa," "binge-eating disorder," "saliva," "biomarkers," "Cortisol," and "Amylases." Boolean operators (AND, OR) were used to combine terms and refine the search results.
Management information
Registered date
| 2025 | Year | 05 | Month | 20 | Day |
Last modified on
| 2026 | Year | 02 | Month | 24 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000066208
