UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000057673 |
|---|---|
| Receipt number | R000065659 |
| Scientific Title | Effects of repeated sprint training on metabolic flexibility in young women |
| Date of disclosure of the study information | 2025/04/22 |
| Last modified on | 2025/04/21 21:32:51 |
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Basic information
Public title
Effects of repeated sprint training on metabolic flexibility in young women
Acronym
Effects of repeated sprint training on metabolic flexibility in young women
Scientific Title
Effects of repeated sprint training on metabolic flexibility in young women
Scientific Title:Acronym
Effects of repeated sprint training on metabolic flexibility in young women
Region
| Japan |
Condition
Condition
Metabolic characteristics in healthy young non-obese women
Classification by specialty
| Not applicable | Adult |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
The objective of this study is to examine the effects of a 6-week repeated sprint training (RST) intervention on metabolic flexibility and intramuscular adipose tissue (IntraMAT) in healthy young non-obese women. Metabolic flexibility will be assessed by measuring the changes in fat oxidation and respiratory quotientat at rest after intake high-fat meal. Menstrual cycle and salivary hormone levels will not be controlled in order to reflect real-world intervention effects.
Basic objectives2
Efficacy
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
The changes in respiratory quotient and fat oxidation after intake high fat meal and IntraMAT of the thigh will be assessed before and after the 6 week intervention. Respiratory quotient and fat oxidation will be calculated from oxygen uptake and carbon dioxide excretion measured by indirect calorimetry during a steady state protocol.
Key secondary outcomes
Base
Study type
Interventional
Study design
Basic design
Parallel
Randomization
Non-randomized
Randomization unit
Blinding
Open -no one is blinded
Control
Active
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
2
Purpose of intervention
Treatment
Type of intervention
| Behavior,custom |
Interventions/Control_1
Participants in the intervention group will perform repeated sprint training (RST) for 6 weeks, three times per week. Each session will last approximately 15 minutes, including warm-up, fifteen 8-second all-out sprints with 12-second rest intervals, and cool-down.
Interventions/Control_2
Participants in the control group will not receive any training intervention and will maintain their usual lifestyle. Measurements will be conducted at the same time points as in the intervention group.
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 18 | years-old | <= |
Age-upper limit
| 29 | years-old | >= |
Gender
Female
Key inclusion criteria
Healthy non-obese women aged 18 to 29 years (BMI 18.5 to 4.9).
No serious medical conditions and able to carry out daily activities.
Able to participate in the scheduled training and measurements.
Key exclusion criteria
History of orthopedic disorders
Currently pregnant or possibly pregnant
Current smoker
Undergoing hormonal therapy
Target sample size
20
Research contact person
Name of lead principal investigator
| 1st name | Akira |
| Middle name | |
| Last name | Ishikawa |
Organization
Nippon Sport Science University
Division name
Faculty of Childhood Sport Education
Zip code
158-8508
Address
7-1-1 Fukazawa, Setagaya-ku, Tokyo 158-8508, Japan
TEL
03-5706-1360
aishikawapan@gmail.com
Public contact
Name of contact person
| 1st name | Akira |
| Middle name | |
| Last name | Ishikawa |
Organization
Nippon Sport Science University
Division name
Faculty of Childhood Sport Education
Zip code
158-8508
Address
7-1-1 Fukazawa, Setagaya-ku, Tokyo 158-8508, Japan
TEL
03-5706-1360
Homepage URL
aishikawapan@gmail.com
Sponsor or person
Institute
Nippon Sport Science University
Institute
Department
Personal name
Funding Source
Organization
Grants-in-Aid for Scientific Research
Organization
Division
Category of Funding Organization
Japanese Governmental office
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Nippon Sport Science University Research Ethics Committee
Address
7-1-1 Fukazawa, Setagaya-ku, Tokyo 158-8508, Japan
Tel
03-5706-1360
aishikawapan@gmail.com
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
日本体育大学（東京都）
Other administrative information
Date of disclosure of the study information
| 2025 | Year | 04 | Month | 22 | Day |
Related information
URL releasing protocol
https://nittaidai.repo.nii.ac.jp/record/2000398/files/2023%E5%B9%B4%E5%BA%A6_%E4%BD%93%E8%82%B2%E7%A
Publication of results
Unpublished
Result
URL related to results and publications
https://nittaidai.repo.nii.ac.jp/record/2000398/files/2023%E5%B9%B4%E5%BA%A6_%E4%BD%93%E8%82%B2%E7%A
Number of participants that the trial has enrolled
28
Results
No significant changes were observed in MF or IntraMAT content in either group. However, the RST group showed a significant increase in total thigh muscle CSA compared with pre-intervention (P < 0.05), with no changes in fat-free fat mass. Metabolic markers including glucose, insulin, and HOMA-IR remained unchanged.
Results date posted
| 2025 | Year | 04 | Month | 21 | Day |
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participants were healthy, non obese women aged 18 to 29 years (BMI 18.5 to 24.9) with no regular exercise habits.
Participant flow
28 participants provided consent and were enrolled. They were assigned to the intervention group (n = 14) or control group (n = 14). All participants completed the 6-week study.
Adverse events
No adverse events were reported.
Outcome measures
Primary outcome: Respiratory quotient, fat oxidation, carbohydrate oxidation, intramuscular adipose tissue (IntraMAT)
Secondary outcomes: Body composition (fat mass, free-fat mass), muscle cross-sectional area (CSA), blood glucose, serum insulin
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Completed
Date of protocol fixation
| 2022 | Year | 04 | Month | 29 | Day |
Date of IRB
| 2022 | Year | 06 | Month | 10 | Day |
Anticipated trial start date
| 2022 | Year | 07 | Month | 08 | Day |
Last follow-up date
| 2023 | Year | 01 | Month | 18 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
Management information
Registered date
| 2025 | Year | 04 | Month | 21 | Day |
Last modified on
| 2025 | Year | 04 | Month | 21 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000065659
