UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000056956 |
|---|---|
| Receipt number | R000065090 |
| Scientific Title | Cell Therapy in Cerebral Palsy: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials |
| Date of disclosure of the study information | 2025/02/06 |
| Last modified on | 2025/02/06 16:43:05 |
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Basic information
Public title
Cell Therapy in Cerebral Palsy: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials
Acronym
Cell Therapy in Cerebral Palsy: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials
Scientific Title
Cell Therapy in Cerebral Palsy: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials
Scientific Title:Acronym
Cell Therapy in Cerebral Palsy
Region
| Japan | Asia(except Japan) | North America |
| South America | Australia | Europe |
| Africa |
Condition
Condition
Cerebral Palsy (CP)
Classification by specialty
| Pediatrics | Child |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
The present systematic review and network meta-analysis aim to synthesize evidence from randomized controlled trials (RCTs) to evaluate the efficacy and safety of cell-based therapies in CP treatment.
Basic objectives2
Safety,Efficacy
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Efficiency
Key secondary outcomes
Base
Study type
Others,meta-analysis etc
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| Not applicable |
Age-upper limit
| 18 | years-old | > |
Gender
Male and Female
Key inclusion criteria
Studies were selected based on the following criteria. Inclusion criteria included: 1) patients diagnosed with CP, 2) RCT, and 3) any cell-based therapy, including but not limited to MSCs, NSCs, and UCB.
Key exclusion criteria
Exclusion criteria included: 1) studies with a sample size of fewer than 10 cases in any arm, 2) crossover studies lacking detailed data at the pre-crossover point, 3) subgroup analyses of previously published studies, and 4) studies in which data could not be extracted.
Target sample size
683
Research contact person
Name of lead principal investigator
| 1st name | Yumeng |
| Middle name | |
| Last name | Zhang |
Organization
Faculty of Medicine, Saga University
Division name
Department of Pediatrics
Zip code
849-8501
Address
5-1-1 Nabeshima, Saga 849-8501, Japan
TEL
952-34-2314
yumeng1990228@gmail.com
Public contact
Name of contact person
| 1st name | Yumeng |
| Middle name | |
| Last name | Zhang |
Organization
Faculty of Medicine, Saga University
Division name
Department of Pediatrics
Zip code
849-8501
Address
5-1-1 Nabeshima, Saga 849-8501, Japan
TEL
952-34-2314
Homepage URL
yumeng1990228@gmail.com
Sponsor or person
Institute
Saga University
Institute
Department
Personal name
Funding Source
Organization
Saga University
Organization
Division
Category of Funding Organization
Self funding
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Saga University IRB
Address
5-1-1 Nabeshima, Saga 849-8501, Japan
Tel
952-34-2314
yumeng1990228@gmail.com
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2025 | Year | 02 | Month | 06 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Preinitiation
Date of protocol fixation
| 2024 | Year | 09 | Month | 01 | Day |
Date of IRB
Anticipated trial start date
| 2025 | Year | 02 | Month | 08 | Day |
Last follow-up date
| 2025 | Year | 08 | Month | 08 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
None
Management information
Registered date
| 2025 | Year | 02 | Month | 06 | Day |
Last modified on
| 2025 | Year | 02 | Month | 06 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000065090
