UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000055758 |
|---|---|
| Receipt number | R000063726 |
| Scientific Title | Impact of antibiotic use in patients after hematopoietic stem cell transplantation on graft-versus-host disease outcomes: a systematic review and meta-analysis |
| Date of disclosure of the study information | 2024/10/15 |
| Last modified on | 2025/04/07 12:13:09 |
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Basic information
Public title
Impact of antibiotic use in patients after hematopoietic stem cell transplantation on graft-versus-host disease outcomes: a systematic review and meta-analysis
Acronym
Impact of antibiotic use in patients after hematopoietic stem cell transplantation on graft-versus-host disease outcomes
Scientific Title
Impact of antibiotic use in patients after hematopoietic stem cell transplantation on graft-versus-host disease outcomes: a systematic review and meta-analysis
Scientific Title:Acronym
Impact of antibiotic use in patients after hematopoietic stem cell transplantation on graft-versus-host disease outcomes
Region
| Japan |
Condition
Condition
graft-versus-host disease
Classification by specialty
| Infectious disease |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
To investigate an impact of antibiotic use in patients after hematopoietic stem cell transplantation on graft-versus-host disease outcomes
Basic objectives2
Safety
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
graft-versus-host disease-related mortality
Key secondary outcomes
Base
Study type
Others,meta-analysis etc
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| Not applicable |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
observational and interventional studies addressing graft-versus-host disease outcomes of antibiotic use in patients after hematopoietic stem cell transplantation
Key exclusion criteria
studies without description of outcome of interest; review articles; conference reports
Target sample size
Research contact person
Name of lead principal investigator
| 1st name | Hiroshi |
| Middle name | |
| Last name | ItIto |
Organization
Tokyo Medical University Ibaraki Medical Center
Division name
Division of General Internal Medicine
Zip code
300-0332
Address
3-20-1, Chuo, Ami-machi, Inashiki-gun, Ibaraki, Japan
TEL
0298871161
itohirokan@yahoo.co.jp
Public contact
Name of contact person
| 1st name | Hiroshi |
| Middle name | |
| Last name | Ito |
Organization
Tokyo Medical University Ibaraki Medical Center
Division name
Division of General Internal Medicine
Zip code
300-0332
Address
3-20-1, Chuo, Ami-machi, Inashiki-gun, Ibaraki, Japan
TEL
0298871161
Homepage URL
itohirokan@yahoo.co.jp
Sponsor or person
Institute
Tokyo Medical University
Institute
Department
Personal name
Funding Source
Organization
Tokyo Medical University
Organization
Division
Category of Funding Organization
Self funding
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
-
Address
-
Tel
0298871161
itohirokan@yahoo.co.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2024 | Year | 10 | Month | 15 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Completed
Date of protocol fixation
| 2024 | Year | 10 | Month | 07 | Day |
Date of IRB
| 2024 | Year | 10 | Month | 07 | Day |
Anticipated trial start date
| 2024 | Year | 10 | Month | 07 | Day |
Last follow-up date
| 2025 | Year | 07 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
In this study, we will conduct a systematic review and meta-analysis of research papers investigating the impact of antibiotic use in patients after hematopoietic stem cell transplantation on outcomes due to graft-versus-host disease. This study complies with PRISMA guidelines.
Management information
Registered date
| 2024 | Year | 10 | Month | 07 | Day |
Last modified on
| 2025 | Year | 04 | Month | 07 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000063726
