UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000054965 |
|---|---|
| Receipt number | R000062755 |
| Scientific Title | The relationship between affiliate stigma and quality of life among parents of children with autism spectrum disorder: A systematic review and meta-analysis |
| Date of disclosure of the study information | 2024/07/15 |
| Last modified on | 2025/05/17 22:17:42 |
* This page includes information on clinical trials registered in UMIN clinical trial registed system.
* We don't aim to advertise certain products or treatments
Basic information
Public title
The relationship between affiliate stigma and quality of life among parents of children with autism spectrum disorder: A systematic review and meta-analysis
Acronym
The relationship between affiliate stigma and quality of life among parents of children with autism spectrum disorder: A systematic review and meta-analysis
Scientific Title
The relationship between affiliate stigma and quality of life among parents of children with autism spectrum disorder: A systematic review and meta-analysis
Scientific Title:Acronym
The relationship between affiliate stigma and quality of life among parents of children with autism spectrum disorder: A systematic review and meta-analysis
Region
| Japan |
Condition
Condition
Autism Spectrum Disorders
Classification by specialty
| Psychiatry |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
The aim of this study is to investigate the strength and nature of the relationship between affiliate stigma and quality of life in parents of children with autism spectrum disorder.
Basic objectives2
Others
Basic objectives -Others
Psychological mechanisms of affiliate stigma and quality of life will also be investigated.
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Electronic database searches use ScienceDirect, PubMed, Web of Science and PsycINFO. Assess the relationship between affiliate stigma and quality of life.
Key secondary outcomes
Base
Study type
Others,meta-analysis etc
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| Not applicable |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
The following search formulae should be used to target the literature obtained.
#1 Affiliate stigma
#2 Stigma
#3 ASD
#4 Autism spectrum
#5 Asperger's
#6 Autistic disorder
#7 Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS)
Key exclusion criteria
Exclude literature that is not suitable for analysis, such as missing data.
Target sample size
Research contact person
Name of lead principal investigator
| 1st name | Wataru |
| Middle name | |
| Last name | Iida |
Organization
The Open University of Japan
Division name
Graduate School of Arts and Sciences
Zip code
261-8586
Address
2-11 Wakaba, Mihama-ku, Chiba City
TEL
043-276-5111
wacharu1214@gmail.com
Public contact
Name of contact person
| 1st name | Wataru |
| Middle name | |
| Last name | Iida |
Organization
The Open University of Japan
Division name
Graduate School of Arts and Sciences
Zip code
261-8586
Address
2-11 Wakaba, Mihama-ku, Chiba City
TEL
043-276-5111
Homepage URL
wacharu1214@gmail.com
Sponsor or person
Institute
The Open University of Japan
Institute
Department
Personal name
Funding Source
Organization
The Open University of Japan
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
The Open University of Japan
Address
2-11 Wakaba, Mihama-ku, Chiba City
Tel
043-276-5111
wacharu1214@gmail.com
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2024 | Year | 07 | Month | 15 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
1996
Results
Affiliate stigma was negatively correlated with quality of life (r = -0.50, 95% CI [-0.58, -0.40]). Heterogeneity was high (I2 = 82.8%). No publication bias was detected. Excluding one impactful study slightly reduced the correlation (r = -0.46) and heterogeneity (I2 = 53.0%).
Results date posted
| 2025 | Year | 05 | Month | 17 | Day |
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Completed
Date of protocol fixation
| 2024 | Year | 07 | Month | 15 | Day |
Date of IRB
| 2024 | Year | 07 | Month | 01 | Day |
Anticipated trial start date
| 2024 | Year | 07 | Month | 15 | Day |
Last follow-up date
| 2024 | Year | 12 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
1.search strategy
Literature searches were conducted using the electronic databases ScienceDirect, PubMed, Web of Science, PsycINFO ( ) and Medline ( ). Several combinations of the following search terms and related phrases were used, separated by Boolean operators OR and AND: "affiliate stigma" OR "stigma" AND "ASD" OR "autism spectrum" OR "Asperger's" OR "autistic disorder" OR "pervasive developmental disorder not otherwise specified (PDD-) NOS)" For the purpose of an extensive exploratory search, search terms for stigma variables were not used (e.g. to avoid excluding relevant articles where the relationship between stigma and quality of life was not the focus of the study). The reference lists of included articles were manually screened to identify additional studies.
2.eligibility criteria
Eligibility criteria were: i) published in English; ii) included participants who were caregivers of children with a primary diagnosis of ASD (autism, Asperger syndrome, pervasive developmental disorder); iii) empirical studies that investigated the cross-sectional or longitudinal association between autism parental stigma and quality of life; vi) including at least one quantitative measure investigated; v) published in a peer-reviewed journal; vi) written in English; and vii) published between 2009 and 2024 (limited to dealing with the most recent data). Studies were included in the meta-analysis if there were sufficient data to calculate effect sizes. Intervention studies and controlled trials were included if they reported on the association between stigma and quality of life in parents with autistic children.
Management information
Registered date
| 2024 | Year | 07 | Month | 15 | Day |
Last modified on
| 2025 | Year | 05 | Month | 17 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000062755
