Unique ID issued by UMIN | UMIN000053645 |
---|---|
Receipt number | R000061121 |
Scientific Title | A survey of nutritional management after gastrointestinal cancer surgery and an association between the parenteral nutritional prescriptions and clinical outcomes: a cohort study using a medical database |
Date of disclosure of the study information | 2024/02/19 |
Last modified on | 2024/11/27 16:02:03 |
A survey of nutritional management after gastrointestinal cancer surgery and an association between the parenteral nutritional prescriptions and clinical outcomes: a cohort study using a medical database
Nutritional management after surgery and clinical outcomes for gastrointestinal cancer patients
A survey of nutritional management after gastrointestinal cancer surgery and an association between the parenteral nutritional prescriptions and clinical outcomes: a cohort study using a medical database
Nutritional management after surgery and clinical outcomes for gastrointestinal cancer patients
Japan |
Patients operated for gastrointestinal cancer surgery under general anesthesia
Gastrointestinal surgery | Hepato-biliary-pancreatic surgery |
Malignancy
NO
To clarify nutritional management in early postoperative period for gastrointestinal cancer patients and to investigate the association between the parenteral nutritional prescription doses and clinical outcomes for patients who are fasting over 7 days after surgery
Efficacy
Postoperative events
In-hospital mortality
Postoperative complication
Activities of daily living
Readmission
Length of stay
Medical costs
Observational
18 | years-old | <= |
Not applicable |
Male and Female
1. Patients operated for gastrointestinal cancer surgery under general anesthesia between January 1, 2011 and December 31, 2022
2. Patients aged 18 years or older
1. Patients whose height or body weight data is missing
2. Patients whose height is less than 100 cm or 200 cm or more
3. Patients whose body weight is less than 10 kg or 200 kg or more
4. Patients who died or were discharged within 7 days after surgery
5. Patients who received oral feeding or enteral nutrition within 7 days after surgery
6. Patients whose doses of parenteral energy was less than 5 kcal/kg/day or 30 kcal/kg/day or more on average from 1 to 7 days after surgery
20000
1st name | Satoru |
Middle name | |
Last name | Kamoshita |
Otsuka Pharmaceutical Factory, Inc.
Medical Affairs Department Research and Development Center
101-0048
2-9 Kanda Tsukasamachi, Chiyoda-ku Tokyo, Japan
03-5217-5954
kamoshitas@otsuka.jp
1st name | Nahoki |
Middle name | |
Last name | Hayashi |
Otsuka Pharmaceutical Factory, Inc.
Medical Affairs Department Research and Development Center
101-0048
2-9 Kanda Tsukasamachi, Chiyoda-ku Tokyo, Japan
03-5217-5954
Hayashi.Nahoki@otsuka.jp
Otsuka Pharmaceutical Factory, Inc.
Otsuka Pharmaceutical Factory, Inc.
Profit organization
Japan
Shiba Palace Clinic Ethics Review Committee
DaiwaA Hamamatsucho Bldg. 6F, 1-9-10, Hamamatsucho, Minato-ku, Tokyo, 105-0013, Japan
03-5408-1599
shiba_palace@s-palace-clinic.com
NO
2024 | Year | 02 | Month | 19 | Day |
Unpublished
18294
From 2011 to 2022, more patients received early oral intake, and fewer patients were received early parenteral nutrition (PN). Energy and amino acid doses prescribed in PN were deficient, and almost no lipid was prescribed. The associations between clinical adverse events and parenteral energy/amino acid doses were investigated. Parenteral energy doses were not associated with clinical adverse events, but amino acid doses were significantly associated with clinical adverse events.
2024 | Year | 11 | Month | 27 | Day |
Completed
2024 | Year | 02 | Month | 08 | Day |
2024 | Year | 02 | Month | 08 | Day |
2024 | Year | 02 | Month | 20 | Day |
2024 | Year | 11 | Month | 06 | Day |
Study design
A cohort study using the medical claims database
Data source
A medical database provided by Medical Data Vision Co. Ltd. The database is based on the DPC data/medical and technical service claims data. The database covers about 27% of all DPC hospitals in Japan. All data is anonymized from the viewpoint of personal information protection.
1. Survey of nutritional management
The nutritional management is surveyed based on the prescription and treatment records available in the database. We analyze the following items.
・Route of nutritional administration
・Situation of nutritional management
・Risk factors for long-term fasting
・Prescribed dose of parenteral nutrition
・Percentage achieving nutritional recommendations by BMI
2. Association between the nutritional prescription doses and clinical outcomes
Patients who are fasting over 7 days after surgery are divided into some groups based on the nutritional prescribed doses. The Association between the nutritional prescription doses and clinical outcomes are investigated by multivariable logistic regression analysis used to estimate odds ratios and the 95% confidence intervals adjusted for patient backgrounds as confounding factors.
2024 | Year | 02 | Month | 19 | Day |
2024 | Year | 11 | Month | 27 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000061121