Unique ID issued by UMIN | UMIN000053544 |
---|---|
Receipt number | R000061101 |
Scientific Title | Investigating how social defeat stress in childhood causes changes in brain function in adulthood using questionnaires and magnetoencephalography. |
Date of disclosure of the study information | 2024/04/01 |
Last modified on | 2024/02/05 11:22:08 |
Investigate how experiences such as childhood abuse and neglect alter brain activity in adulthood.
Investigating whether adverse childhood experiences alter brain activity in adulthood.
Investigating how social defeat stress in childhood causes changes in brain function in adulthood using questionnaires and magnetoencephalography.
Investigating how SDS in childhood causes changes in brain function in adulthood using questionnaires and MEG.
Japan |
Healthy adults
Adult |
Others
NO
The purpose of this study is to use MEG to determine how excessive adverse childhood experiences alter brain activity at rest and during pain perception in adulthood.
Others
Neurophysiological mechanisms
Resting brain activity will be measured using MEG. Furthermore, brain activity will be measured on a region-by-region basis with greater precision using MRI images of the individual. The Childhood Trauma Questionnaire-Short Form(CTQ-SF) will then be used to assess social defeat stress (SDS) experienced in childhood. The Brief Resilience Scale and the Connor-Davidson Resilience Scale will be used to assess stress tolerance. Additionally, the Beck Depression Inventory (BDI), a measure of depression, and the State-Trait Anxiety Inventory (STAI), a measure of anxiety, will be used to assess current mood. For pain assessment, thermal pain threshold and thermal pain tolerance threshold will be measured using a thermal stimulator.
Observational
18 | years-old | <= |
27 | years-old | >= |
Male and Female
Healthy adults
pregnant
dialysis patient
taking neuromodulatory medication
presence of a metal or electric implant
history of neurological or psychiatric disorder
100
1st name | Sota |
Middle name | |
Last name | Inoue |
Niigata University of Health and Welfare
Institute for Human Movement and Medical Sciences
950-3198
1398 Shimami-cho, Kita-ku, Niigata City, Niigata, Japan
025-257-4455
hwd23015@nuhw.ac.jp
1st name | Sota |
Middle name | |
Last name | Inoue |
Niigata University of Health and Welfare
Institute for Human Movement and Medical Science
950-3198
1398 Shimami-cho, Kita-ku, Niigata City, Niigata, Japan
025-257-4455
hwd23015@nuhw.ac.jp
Niigata University of Health and Welfare
Niigata University of Health and Welfare
Other
Niigata University of Health and Welfare
1398 Shimami-cho, Kita-ku, Niigata City, Niigata, Japan
025-257-4455
hwd23015@nuhw.ac.jp
NO
2024 | Year | 04 | Month | 01 | Day |
Unpublished
Preinitiation
2024 | Year | 02 | Month | 01 | Day |
2024 | Year | 05 | Month | 01 | Day |
2027 | Year | 03 | Month | 31 | Day |
Examine how childhood stress affects brain activity in adulthood.
2024 | Year | 02 | Month | 05 | Day |
2024 | Year | 02 | Month | 05 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000061101
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |