Unique ID issued by UMIN | UMIN000052298 |
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Receipt number | R000059696 |
Scientific Title | Prenatal exposure to intra-amniotic infection with Ureaplasma species increases the prevalence of bronchopulmonary dysplasia. |
Date of disclosure of the study information | 2023/09/25 |
Last modified on | 2023/09/25 12:31:14 |
Prenatal exposure to intra-amniotic infection with Ureaplasma species increases the prevalence of bronchopulmonary dysplasia.
Prenatal exposure to intra-amniotic infection with Ureaplasma species increases the prevalence of bronchopulmonary dysplasia.
Prenatal exposure to intra-amniotic infection with Ureaplasma species increases the prevalence of bronchopulmonary dysplasia.
Prenatal exposure to intra-amniotic infection with Ureaplasma species increases the prevalence of bronchopulmonary dysplasia.
Japan |
Intra-amniotic infection
Obstetrics and Gynecology |
Others
NO
The present study investigated the relationship between bronchopulmonary dysplasia (BPD) and intra-amniotic infection with Ureaplasma species.
Others
The present study investigated the relationship between adverse neonatal outcomes and intra-amniotic infection with Ureaplasma species.
Exploratory
Explanatory
Not applicable
The primary study outcomes were the relationships between the prevalence of BPD and intra-amniotic infection with or without Ureaplasma spp. and intra-amniotic inflammation without MIAC after adjusting for gestational age at birth.
Secondary study outcomes were the relationships between the prevalence of adverse neonatal outcomes, and intra-amniotic infection with or without Ureaplasma spp. and intra-amniotic inflammation without MIAC after adjusting for potential confounders.
Observational
Not applicable |
Not applicable |
Female
Patients with singleton pregnancies (between August 2014 and April 2020) who underwent inpatient management at our department for PPROM, preterm labor, cervical insufficiency, and asymptomatic cervical shortening between 22 weeks 0 days and 33 weeks 6 days of gestation were included.
Exclusion criteria were as follows: delivery after 34 gestational weeks, fetal chromosomal abnormalities or multiple malformations, intrauterine fetal death, delivery at another hospital, MIAC in which Ureaplasma spp. and Mycoplasma hominis were not identified, and an unclear placental pathology or umbilical vein blood interleukin (IL)-6 concentration in patients in whom intra-amniotic inflammation or MIAC was not detected by amniocentesis or for whom amniocentesis was not indicated.
209
1st name | Makoto |
Middle name | |
Last name | Nomiyama |
National Hospital Organization, Saga National Hospital
Department of Obstetrics and Gynecology
849-8577
Hinode 1-20-1, Saga, Japan
0952307141
nomiyama8522@gmail.com
1st name | Makoto |
Middle name | |
Last name | Nomiyama |
National Hospital Organization, Saga National Hospital
Department of Obstetrics and Gynecology
849-8577
Hinode 1-20-1, Saga, Japan
0952307141
nomiyama8522@gmail.com
National Hospital Organization, Saga National Hospital
Makoto Nomiyama
National Hospital Organization Saga National Hospital
Other
Japan
The Institutional Review Board of the National Hospital Organization Saga National Hospital
Hinode 1-20-1, Saga, Japan
0952307141
shouno.mitsuaki.np@mail.hosp.go.jp
NO
国立病院機構佐賀病院
2023 | Year | 09 | Month | 25 | Day |
Unpublished
209
Completed
2022 | Year | 06 | Month | 08 | Day |
2022 | Year | 06 | Month | 09 | Day |
2022 | Year | 06 | Month | 10 | Day |
2022 | Year | 12 | Month | 10 | Day |
2023 | Year | 03 | Month | 31 | Day |
2023 | Year | 04 | Month | 30 | Day |
2023 | Year | 05 | Month | 31 | Day |
Intra-amniotic infection with Ureaplasma spp. was diagnosed in 37 patients, intra-amniotic infection without Ureaplasma spp. in 28, intra-amniotic inflammation without MIAC in 58, and preterm birth without MIR/FIR and FIRS in 86.After adjusting for potential confounders, a logistic regression analysis was performed to investigate the relationships between BPD, adverse neonatal outcomes, and intra-amniotic infection with and without Ureaplasma spp. and intra-amniotic inflammation without MIAC.
2023 | Year | 09 | Month | 25 | Day |
2023 | Year | 09 | Month | 25 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000059696
Research Plan | |
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Registered date | File name |
2023/09/25 | 5.後ろ向き研究計画書 - 性器マイコプラズマ子宮内感染 UMIN ICDR.doc |
Research case data specifications | |
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Registered date | File name |
2023/09/25 | データ仕様書.docx |
Research case data | |
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Registered date | File name |
2023/09/25 | UMIN ICDR0925.xlsx |
Value
https://center6.umin.ac.jp/ice/59696