UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000049008 |
|---|---|
| Receipt number | R000055832 |
| Scientific Title | A systematic review and meta-analysis of the usefulness of de-escalation in hospital acquired pneumonia |
| Date of disclosure of the study information | 2022/09/24 |
| Last modified on | 2023/03/25 14:21:45 |
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Basic information
Public title
A systematic review and meta-analysis of the usefulness of de-escalation in hospital acquired pneumonia
Acronym
A systematic review and meta-analysis of the usefulness of de-escalation in hospital acquired pneumonia
Scientific Title
A systematic review and meta-analysis of the usefulness of de-escalation in hospital acquired pneumonia
Scientific Title:Acronym
A systematic review and meta-analysis of the usefulness of de-escalation in hospital acquired pneumonia
Region
| Japan |
Condition
Condition
hospital-acquired pneumonia
Classification by specialty
| Pneumology | Infectious disease |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
To examine the benefits and harms of de-escalation in the practice of hospital-acquired pneumonia.
Basic objectives2
Safety,Efficacy
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
The cure rate of pneumonia
Key secondary outcomes
Mortality assessed in each study, the rate of readmission, the occurrence of drug-resistant pathogens, duration of hospital stay, the frequency of adverse events, medical expenses.
Base
Study type
Others,meta-analysis etc
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 18 | years-old | <= |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
Patients with hospital-acquired pneumonia are defined by the 2017 JRS guidelines or hospital-acquired pneumonia is defined by the 2016 ATS/IDSA guidelines.
Key exclusion criteria
Pediatric patients
Target sample size
Research contact person
Name of lead principal investigator
| 1st name | Naoki |
| Middle name | |
| Last name | Iwanaga |
Organization
Nagasaki University Hospital
Division name
Department of Respiratory Medicine
Zip code
8528501
Address
Sakamoto 1-7-1, Nagasaki City
TEL
095-819-7273
niwanaga@nagasaki-u.ac.jp
Public contact
Name of contact person
| 1st name | Naoki |
| Middle name | |
| Last name | Iwanaga |
Organization
Nagasaki University Hospital
Division name
Department of Respiratory Medicine
Zip code
8528501
Address
Sakamoto 1-7-1, Nagasaki City
TEL
095-819-7273
Homepage URL
niwanaga@nagasaki-u.ac.jp
Sponsor or person
Institute
Systematic review team of Japanese clinical practice guidelines of pneumonia, 2022
Institute
Department
Personal name
Funding Source
Organization
Not applicable
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Not applicable
Address
Not applicable
Tel
Not applicable
Not applicable
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2022 | Year | 09 | Month | 24 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Preinitiation
Date of protocol fixation
| 2022 | Year | 09 | Month | 21 | Day |
Date of IRB
Anticipated trial start date
| 2022 | Year | 09 | Month | 23 | Day |
Last follow-up date
| 2022 | Year | 12 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
A systematic search of the literature will be conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) statement. The Cochrane Central Register of Controlled Trials (CENTRAL), Pubmed, and EMBASE will be used as electronic databases.
Management information
Registered date
| 2022 | Year | 09 | Month | 23 | Day |
Last modified on
| 2023 | Year | 03 | Month | 25 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000055832
| Research Plan | |
|---|---|
| Registered date | File name |
| Research case data specifications | |
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| Registered date | File name |
| Research case data | |
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| Registered date | File name |
