Unique ID issued by UMIN | UMIN000048965 |
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Receipt number | R000055787 |
Scientific Title | Clinical characteristics of Frontotemporal lobar degeneration with tau pathology |
Date of disclosure of the study information | 2022/09/20 |
Last modified on | 2024/03/22 14:29:00 |
Clinical characteristics of Frontotemporal lobar degeneration with tau pathology
Clinical characteristics of Frontotemporal lobar degeneration with tau pathology
Clinical characteristics of Frontotemporal lobar degeneration with tau pathology
Clinical characteristics of Frontotemporal lobar degeneration with tau pathology
Japan |
Frontotemporal lobar degeneration
Psychiatry |
Others
NO
FTLD patients will be classified into tau-positive and tau-negative groups based on tau PET imaging findings. This study aims to characterize the clinical features and the neuroimaging biomarkers specific to the tau-positive group.
Others
Exploratory research
Exploratory
Clinical characteristics
Mini-Mental State Examination (MMSE), Frontal Assessment Battery (FAB), Addenbrooke's Cognitive Examination (ACE-R), Western Aphasia Battery (WAB), Neuropsychiatric Inventory (NPI), Stereotypy Rating Inventory (SRI), Cambridge Behavioral Inventory (CBI), Everyday Memory Checklist (EMC), Geriatric depression scale (GDS), the Lawton Instrumental Activities of Daily Living Scale (IADL), Physical Self-Maintenance Scale (PSMS), Clinical Dementia Rating (CDR), cranial MRI, brain SPECT
Interventional
Parallel
Non-randomized
Open -no one is blinded
No treatment
2
Diagnosis
Other |
tau-positive group
tau-negative group
35 | years-old | <= |
90 | years-old | > |
Male and Female
Those who have at least one symptom of Possible bvFTD in the international diagnostic criteria for bvFTD (Rascovsky K et al, 2011) or at least one verbal symptom in Neary's diagnostic criteria for SD/PNFA (Neary D et al, 1998) and are suspected to have FTLD.
Those whose age is 35 years old or older and less than 90 years old at the time of consent.
Those who have given written consent to participate.
Women who are during pregnancy or breastfeeding.
Those who have cerebrovascular disorders that may affect the results of tau PET.
Those who are judged to be inappropriate for participation in this clinical study.
125
1st name | Manabu |
Middle name | |
Last name | Ikeda |
Osaka University Graduate School of Medicine
Department of Psychiatry
565-0871
2-2, Yamadaoka, Suita, Osaka, Japan
0668793051
mikeda@psy.med.osaka-u.ac.jp
1st name | Shunsuke |
Middle name | |
Last name | Sato |
Osaka University Graduate School of Medicine
Department of Psychiatry
565-0871
2-2, Yamadaoka, Suita, Osaka, Japan
0668793051
sato@psy.med.osaka-u.ac.jp
Osaka University
Ministry of Education, Culture, Sports, Science and Technology
Japanese Governmental office
Osaka University Clinical Research Review Committee
2-2, Yamadaoka, Suita, osaka, japan
0662108296
rinri@hp-crc.med.osaka-u.ac.jp
NO
2022 | Year | 09 | Month | 20 | Day |
Unpublished
Enrolling by invitation
2022 | Year | 09 | Month | 20 | Day |
2022 | Year | 11 | Month | 07 | Day |
2022 | Year | 11 | Month | 07 | Day |
2027 | Year | 03 | Month | 31 | Day |
2022 | Year | 09 | Month | 19 | Day |
2024 | Year | 03 | Month | 22 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000055787
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