Unique ID issued by UMIN | UMIN000047781 |
---|---|
Receipt number | R000054472 |
Scientific Title | Elucidation of biological mechanisms of pathological grief in a longitudinal investigation |
Date of disclosure of the study information | 2022/05/17 |
Last modified on | 2024/06/28 21:55:31 |
Understaning of mechanisms in coping with grief after bereavement
Mechanisms in coping with grief
Elucidation of biological mechanisms of pathological grief in a longitudinal investigation
Biological mechanisms of grief
Japan |
Prolonged grief disorder
Psychiatry |
Others
YES
Pathological factors
Others
Etiology
Brain functional and structural imaging measures
Salivary inflammatory markers, salivary oxytocin concentration, oxytocin receptor DNA methylation polymorphism, heart rate variability, physical activity, grief symptoms, depression symptoms, anxiety symptoms, posttraumatic stress symptoms, quality of life, sleep quality, daytime sleepiness, pain empathy, attachment style, post-traumatic growth
Observational
20 | years-old | <= |
Not applicable |
Male and Female
1) Aged 20 years or older
2) Bereaved of a significant other (a family member, relative, friend, or partner)
3) Bereaved for more than 12 months
4) Capable to provide informed consent
5) MRI indicated
1) Any psychiatric disorders excluding prolonged grief disorder, depressive disorders, posttraumatic stress disorder, or anxiety disorders
2) Substance-related disorders within 6 months
3) Self-harm or suicide attempt within 6 months
4) A score less than 24 on Mini-Mental State Examination
5) Neurological disorders
6) Pregnancy
90
1st name | Takuya |
Middle name | |
Last name | Yoshiike |
National Center of Neurology and Psychiatry
Department of Sleep-Wake Disorders, National Institute of Mental Health
187-8553
4-1-1 Ogawahigashi, Kodaira, Tokyo
042-346-2071
yoshiike@ncnp.go.jp
1st name | Takuya |
Middle name | |
Last name | Yoshiike |
National Center of Neurology and Psychiatry
Department of Sleep-Wake Disorders, National Institute of Mental Health
187-8553
4-1-1 Ogawahigashi, Kodaira, Tokyo
042-346-2071
https://sites.google.com/view/pgdbiostudy/
yoshiike@ncnp.go.jp
National Center of Neurology and Psychiatry
Japan Society for the Promotion of Science
Japanese Governmental office
Ethical Committee of National Center of Neurology and Psychiatry
4-1-1 Ogawahigashi, Kodaira, Tokyo
042-346-2071
rinri-jimu@ncnp.go.jp
NO
2022 | Year | 05 | Month | 17 | Day |
Unpublished
Open public recruiting
2022 | Year | 03 | Month | 15 | Day |
2022 | Year | 03 | Month | 22 | Day |
2022 | Year | 05 | Month | 10 | Day |
2026 | Year | 03 | Month | 31 | Day |
None
2022 | Year | 05 | Month | 17 | Day |
2024 | Year | 06 | Month | 28 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000054472