Unique ID issued by UMIN | UMIN000046629 |
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Receipt number | R000053193 |
Scientific Title | A Prospective Multicenter Cohort Study on the Safety and Efficacy of Lusutrombopag during Hemostatic Procedures in Chronic Liver Disease |
Date of disclosure of the study information | 2022/01/14 |
Last modified on | 2024/01/23 17:12:42 |
A Prospective Multicenter Cohort Study on the Safety and Efficacy of Lusutrombopag during Hemostatic Procedures in Chronic Liver Disease
Safety and Efficacy Study of Lusutrombopag
A Prospective Multicenter Cohort Study on the Safety and Efficacy of Lusutrombopag during Hemostatic Procedures in Chronic Liver Disease
Safety and Efficacy Study of Lusutrombopag
Japan |
Hepatocellular Carcinoma
Hepato-biliary-pancreatic medicine |
Malignancy
NO
To prospectively enroll patients with chronic liver disease who are scheduled for a wait-and-see hematologic procedure and who will receive lusutrombopag for low platelets, and to evaluate the therapeutic efficacy and safety of treatment for bleeding upon treatment.
Safety,Efficacy
Transfusion avoidance rate during procedures performed approximately 2 weeks after administration
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Prevention
Medicine |
Lusutrombopag 3 mg was administered once a day for 7 days
20 | years-old | <= |
Not applicable |
Male and Female
Patients with low PLT levels (less than 50,000 PLT mcL-1) scheduled for RFA.
Patients whose PLT count tended to decline, cases where the PLT count just before administration was more than 50,000, cases that had previously recorded less than 50,000, and those that fluctuated around 50,000, or were greater than, but around, 50,000.
None
80
1st name | Hideo |
Middle name | |
Last name | Yoshida |
Japanese Red Cross Medical Center
Department of Gastroenterology and Hepatology
150-8935
4-1-22 Hiro-o Shibuya-ku Tokyo
03-3400-1311
yoshida_hideo@med.jrc.or.jp
1st name | Hideo |
Middle name | |
Last name | Yoshida |
Japanese Red Cross Medical Center
Department of Gastroenterology and Hepatology
150-8935
4-1-22 Hiro-o Shibuya-ku Tokyo
0334001311
yoshida_hideo@med.jrc.or.jp
Japanese Red Cross Medical Center
Japanese Red Cross Medical Center
Other
Japanese Red Cross Medical Center
4-1-22 Hiro-o Shibuya-ku Tokyo
0334001311
yoshida_hideo@med.jrc.or.jp
NO
2022 | Year | 01 | Month | 14 | Day |
Partially published
Main results already published
2018 | Year | 02 | Month | 07 | Day |
2018 | Year | 03 | Month | 07 | Day |
2018 | Year | 03 | Month | 07 | Day |
2028 | Year | 03 | Month | 31 | Day |
Part of results are published
2022 | Year | 01 | Month | 13 | Day |
2024 | Year | 01 | Month | 23 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000053193
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