UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000050267 |
|---|---|
| Receipt number | R000052649 |
| Scientific Title | Effect of timing of exercise on postprandial glucose concentration |
| Date of disclosure of the study information | 2023/02/09 |
| Last modified on | 2026/08/12 10:33:37 |
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Basic information
Public title
Effect of timing of exercise on postprandial glucose concentration
Acronym
Effect of timing of exercise on postprandial glucose concentration
Scientific Title
Effect of timing of exercise on postprandial glucose concentration
Scientific Title:Acronym
Effect of timing of exercise on postprandial glucose concentration
Region
| Japan |
Condition
Condition
Healthy adults
Classification by specialty
| Adult |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
The present study aimed to examine the effect of timing and exercise duration on post-meal low exercise after breakfast on postprandial glucose and insulin concentration in young healthy women.
Basic objectives2
Efficacy
Basic objectives -Others
Trial characteristics_1
Others
Trial characteristics_2
Pragmatic
Developmental phase
Not applicable
Assessment
Primary outcomes
postprandial glucose concentration
Key secondary outcomes
serum insulin concenetration
Base
Study type
Interventional
Study design
Basic design
Cross-over
Randomization
Randomized
Randomization unit
Individual
Blinding
Open -no one is blinded
Control
Dose comparison
Stratification
NO
Dynamic allocation
NO
Institution consideration
Blocking
NO
Concealment
Intervention
No. of arms
3
Purpose of intervention
Educational,Counseling,Training
Type of intervention
| Behavior,custom |
Interventions/Control_1
Participants started step exercise for 10 min or for 5 min at 30 min after breakfast or no exercise (control) after consuming breakfast in randomized cross-over. Blood glucose and insulin concentrations are examined at 0, 30, 60, and 120 min.
Interventions/Control_2
Participants started step exercise for 10 min or for 5 min at 30 min after breakfast or no exercise (control) after consuming breakfast in randomized cross-over. Blood glucose and insulin concentrations are examined at 0, 30, 60, and 120 min.
Interventions/Control_3
Participants started step exercise for 10 min or for 5 min at 30 min after breakfast or no exercise (control) after consuming breakfast in randomized cross-over. Blood glucose and insulin concentrations are examined at 0, 30, 60, and 120 min.
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 20 | years-old | <= |
Age-upper limit
| 30 | years-old | >= |
Gender
Female
Key inclusion criteria
1. Healthy adults
2. Individuals written informed consents have been obtained
3. Individuals who are judged appropriate for the study by the principal
Key exclusion criteria
1. Patients with type 1 and type 2 diabetes
2. Treatment with steroid
3. Women with possibility of pregnancy or pregnant
4. Severe health problems not suitable for the study
Target sample size
23
Research contact person
Name of lead principal investigator
| 1st name | Saeko |
| Middle name | |
| Last name | Imai |
Organization
Kyoto Women's University
Division name
Food and Nutrrition
Zip code
6058501
Address
35, Imakumano, Kitahiyoshi-cho, HIgashiyama-ku, Kyoto
TEL
+81755317128
imais@kyoto-wu.ac.jp
Public contact
Name of contact person
| 1st name | Saeko |
| Middle name | |
| Last name | Imai |
Organization
Kyoto Women's University
Division name
Food and Nutrrition
Zip code
6058501
Address
35, Imakumano, Kitahiyoshi-cho, HIgashiyama-ku, Kyoto
TEL
0755317128
Homepage URL
imais@kyoto-wu.ac.jp
Sponsor or person
Institute
Kyoto Women's University
Institute
Department
Personal name
Funding Source
Organization
Kyoto Women's University
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Japan
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Kyoto Women's University
Address
35, Imakumano, Kitahiyoshi-cho, HIgashiyama-ku, Kyoto
Tel
+81755317128
imais@kyoto-wu.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
京都女子大学(京都）
Other administrative information
Date of disclosure of the study information
| 2023 | Year | 02 | Month | 09 | Day |
Related information
URL releasing protocol
http://hdl.handle.net/11173/3979
Publication of results
Published
Result
URL related to results and publications
http://hdl.handle.net/11173/3979
Number of participants that the trial has enrolled
23
Results
The purpose of this randomized controlled crossover study is to examine the effect of post-meal timing of short-time low-intensity exercise on postprandial blood glucose concentration in young healthy women as a pilot study for patients with type 2 diabetes. The results suggest that postprandial short-time (10 min) low-intensity step exercise at 30 min of post-meal is effective in suppressing postprandial blood glucose elevation in young healthy women.
Results date posted
| 2026 | Year | 08 | Month | 12 | Day |
Results Delayed
Results Delay Reason
We are writing the paper, soon we will submit our paper to the journal.
Date of the first journal publication of results
| 2025 | Year | 02 | Month | 28 | Day |
Baseline Characteristics
The characteristics of the 23 young healthy women were as follows: height, 160.6 cm, body weight, 52.1 kg, BMI, 20.1, systolic blood pressure, 104 mmHg, diastolic blood pressure, 64 mmHg, fasting plasma glucose, 87 mg/dL, and HbA1c, 5.3%. Data are presented as median.
Participant flow
Participants consumed the test meal within 5 min on three non-consecutive days. On each study day, participants performed either no postprandial exercise or 10 min of step exercise initiated 15 or 30 min after the start of the meal. Postprandial blood glucose levels were measured using self-monitoring of blood glucose.
The intensity of the step exercise was individually prescribed to achieve 30% of the heart rate reserve (HRR), calculated using the Karvonen formula. The step rate was determined for each participant based on the corresponding target heart rate.
Adverse events
No adverse events were observed.
Outcome measures
Immediately after exercise, the increase in blood glucose was attenuated. At 45 min after the start of the meal, the mean blood glucose concentration was significantly lower in the exercise-at-30-min group than in the no-exercise and exercise-at-15-min groups. In addition, the incremental area under the glucose curve (iAUC) at 60 min after the start of the meal was significantly lower in both the exercise-at-15-min and exercise-at-30-min groups than in the no-exercise group, and tended to be lower in the exercise-at-30-min group than in the exercise-at-15-min group. The mean blood glucose concentrations in the exercise-at-15-min and exercise-at-30-min groups and the maximum blood glucose concentration in the exercise-at-15-min group tended to be lower than those in the no-exercise group.
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Completed
Date of protocol fixation
| 2021 | Year | 10 | Month | 30 | Day |
Date of IRB
| 2021 | Year | 10 | Month | 18 | Day |
Anticipated trial start date
| 2021 | Year | 11 | Month | 01 | Day |
Last follow-up date
| 2023 | Year | 06 | Month | 30 | Day |
Date of closure to data entry
| 2023 | Year | 07 | Month | 10 | Day |
Date trial data considered complete
| 2023 | Year | 07 | Month | 15 | Day |
Date analysis concluded
| 2023 | Year | 10 | Month | 31 | Day |
Other
Other related information
Management information
Registered date
| 2023 | Year | 02 | Month | 08 | Day |
Last modified on
| 2026 | Year | 08 | Month | 12 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000052649
