UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000046024 |
|---|---|
| Receipt number | R000052527 |
| Scientific Title | Evaluation of CD271 expression as a prognostic factor in non-small cell lung cancer patients |
| Date of disclosure of the study information | 2021/11/10 |
| Last modified on | 2021/11/10 09:27:05 |
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Basic information
Public title
Evaluation of CD271 expression as a prognostic factor in non-small cell lung cancer patients
Acronym
Evaluation of CD271 expression as a prognostic factor in non-small cell lung cancer patients
Scientific Title
Evaluation of CD271 expression as a prognostic factor in non-small cell lung cancer patients
Scientific Title:Acronym
Evaluation of CD271 expression as a prognostic factor in non-small cell lung cancer patients
Region
| Japan |
Condition
Condition
Non-small cell lung cancer
Classification by specialty
| Chest surgery |
Classification by malignancy
Malignancy
Genomic information
NO
Objectives
Narrative objectives1
The purpose of this study was to evaluate the relationship between the expression of CD271, a nerve growth factor receptor, and prognosis in patients with non-small cell lung cancer treated with surgical resection.
Basic objectives2
Others
Basic objectives -Others
We investigate the relationship between the expression of CD271 in non-small cell lung cancer cells and clinicopathological findings.
Trial characteristics_1
Exploratory
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Recurrence-free survival (RFS)
Key secondary outcomes
Overall survival (OS)
Association between CD271 staining intensity and clinicopathological findings in non-small cell lung cancer
Relationship between the staining intensity of CD271 and the staining intensity of nerve growth factor receptor (NGF, BDGF, Neutrophin) and cancer stromal fibroblast marker molecules (alfa smooth muscle Actin, podoplanin)
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 20 | years-old | <= |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
Non-small cell lung cancer patients who were underwent surgical resection at the Department of Respiratory Surgery, Shiga University of Medical Science Hospital from January 1, 2008 to December 31, 2019
Key exclusion criteria
Patients who have refused to allow their samples and information to be used in this research
Target sample size
200
Research contact person
Name of lead principal investigator
| 1st name | |
| Middle name | |
| Last name | Keiko Ueda |
Organization
Shiga University of Medical Science
Division name
Department of Thoracic Surgery
Zip code
5202192
Address
Seta Tsukinowa-cho, Otsu, Shiga
TEL
0775482244
hqsurg2@belle.shiga-med.ac.jp
Public contact
Name of contact person
| 1st name | Keiko |
| Middle name | Ueda |
| Last name | Ueda |
Organization
Shiga University of Medical Science
Division name
Department of Thoracic Surgery
Zip code
5202192
Address
Seta Tsukinowa-cho, Otsu, Shiga
TEL
0775482244
Homepage URL
hqsurg2@belle.shiga-med.ac.jp
Sponsor or person
Institute
Shiga University of Medical Science
Institute
Department
Personal name
Funding Source
Organization
Shiga University of Medical Science
Organization
Division
Category of Funding Organization
Self funding
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Shiga University of Medical Science
Address
Seta Tsukinowa-cho, Otsu, Shiga
Tel
0775482244
hqsurg2@belle.shiga-med.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2021 | Year | 11 | Month | 10 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Open public recruiting
Date of protocol fixation
| 2021 | Year | 09 | Month | 15 | Day |
Date of IRB
| 2021 | Year | 09 | Month | 15 | Day |
Anticipated trial start date
| 2021 | Year | 09 | Month | 15 | Day |
Last follow-up date
| 2028 | Year | 12 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
https://rinri.shiga-med.ac.jp/rinri/publish_document.aspx?ID=1539
Management information
Registered date
| 2021 | Year | 11 | Month | 10 | Day |
Last modified on
| 2021 | Year | 11 | Month | 10 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000052527
