Unique ID issued by UMIN | UMIN000053767 |
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Receipt number | R000052008 |
Scientific Title | Reliability and validity of cough peak flow measurement with myasthenia gravis |
Date of disclosure of the study information | 2024/03/04 |
Last modified on | 2024/03/04 05:26:40 |
Reliability and validity of cough peak flow measurement with myasthenia gravis
Reliability and validity of cough peak flow measurement with myasthenia gravis
Reliability and validity of cough peak flow measurement with myasthenia gravis
Reliability and validity of cough peak flow measurement with myasthenia gravis
Japan |
myasthenia gravis
Neurology | Rehabilitation medicine | Adult |
Others
NO
The purpose of this study was to clarify the association between the reliability of CPF measurement for MG patients and respiratory function and comprehensive assessment of MG. if the reliability and validity of CPF measurement for MG patients are clarified, MG symptoms related to respiratory function can be easily understood. If the reliability and validity of CPF measurement in MG patients can be clarified, it will provide a simple way to assess MG symptoms related to respiratory function. This study is clinically meaningful because it will provide a convenient evaluation index that can be performed by patients themselves at the bedside or at home, and it may enable appropriate treatment at the right time even if acute exacerbation of MG symptoms occurs.
Others
reliability and validity
Cough peak flow measurement
Assessment at the time of admission and at the time of discharge
1) Pulmonary function tests (FVC, FVE1.0, IC, PEFR)
2) MG comprehensive assessment (QMG score, MG composite, MG ADL)
3) Whether or not self expectoration is possible (judged by the necessity of endotracheal suctioning)
Observational
20 | years-old | <= |
Not applicable |
Male and Female
In this study, patients who fulfill all of the following criteria will be included.
1) MG patients who were admitted to our hospital and underwent rehabilitation between January 2015 and December 2020
2) Patients who are 20 years old or older
3) Patients who have given consent for CPF measurement
(1) Patients who are unable to follow instructions due to impaired consciousness, dementia, or psychiatric symptoms
(2) Patients with poor control of subjective symptoms such as dyspnea and pain
23
1st name | Yoshitaka |
Middle name | |
Last name | Yamanaka |
Chiba University Hospital
Urayasu Rehabilitation Education Center
279-0023
7-2-32 Takasu, Urayasu, Chiba
047-312-6765
y-yama@hospital.chiba-u.jp
1st name | Ryota |
Middle name | |
Last name | Kuroiwa |
Chiba University Hospital
Division of rehabilitation medicine
260-8677
1-8-1 Inohana Chuo-ku, Chiba city
043-222-7171
pseudoarthrosis7@chiba-u.jp
Chiba University Hospital
No funding source
Other
Independent Ethics Committee of Graduate School of Medicine and School of Medicine, Chiba University
1-8-1 Inohana Chuo-ku, Chiba city
043-226-2501
igaku-kouhou@chiba-u.jp
NO
2024 | Year | 03 | Month | 04 | Day |
https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000052008
Unpublished
no yet
26
The intraclass correlation coefficient was more than 0.95 for pre-and post-treatment. Positive correlations were found between CPF and almost all spirometric values as well as between the differences of pre-and post-treatment in CPF and quantitative myasthenia gravis.
2024 | Year | 03 | Month | 04 | Day |
MG patients (n = 26)
Age (years) 55.1 (19.5)
Gender (male/female) 7/19
Height (cm) 158.3 (7.8)
Weight (kg) 57.4 (10.2)
Information was collected from medical record entries for a retrospective observational study.
No adverse events
CPF, respiratory function tests, MG comprehensive evaluation
No longer recruiting
2021 | Year | 01 | Month | 21 | Day |
2021 | Year | 03 | Month | 04 | Day |
2021 | Year | 03 | Month | 04 | Day |
2021 | Year | 07 | Month | 31 | Day |
During data analysis
2024 | Year | 03 | Month | 04 | Day |
2024 | Year | 03 | Month | 04 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000052008
Research Plan | |
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Registered date | File name |
2024/03/04 | MG CPF計画書20201225.dotx |
Research case data specifications | |
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Registered date | File name |
Research case data | |
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Registered date | File name |