Unique ID issued by UMIN | UMIN000044400 |
---|---|
Receipt number | R000050542 |
Scientific Title | Registry of female precocious puberty, aiming identification of predisposing factors, optimization of treatment strategy, and elucidation of prognosis |
Date of disclosure of the study information | 2021/06/03 |
Last modified on | 2022/06/04 16:16:29 |
Registry of female precocious puberty, aiming identification of predisposing factors, optimization of treatment strategy, and elucidation of prognosis
Precocious puberty registry
Registry of female precocious puberty, aiming identification of predisposing factors, optimization of treatment strategy, and elucidation of prognosis
Precocious puberty registry
Japan |
female central precocious puberty
Endocrinology and Metabolism | Pediatrics |
Others
NO
Prospective patient registry, for girls with central precocious puberty, will be constructed.
Others
This study will register prospectively the consecutive female patients with central precocious puberty evaluated at Showa University Hospital. Data obtained from a large number of patients will contribute to reveal the predisposing factors. Analysis of long-term treatment will be useful to develop clinical guideline in future.
Others
Others
Not applicable
1) Information collected at the time of diagnosis: family history, maternal information during pregnancy, perinatal history, past history, social history, growth data, physical findings, endocrine test (LH, FSH, E2, DHEA-S, TSH, Free T3, Free T4, IGF-1), Bone age, ultrasonic findings of uterus and ovary, MRI findings in hypothalamo-pituitary region
2) Information collected during follow-up or treatment
For non-treatment patients: growth data, physical findings, bone age (every 6 months to 1 year until menarche)
For patients with LHRH analog treatment: growth data, physical findings, endocrine test, bone age, ultrasonic findings, treatment details
3) Information to be collected after the completion of treatment
growth data, physical findings, endocrine tests, ultrasonography (6-months and one year following the cessation)
Serum will be cryopreserved for each patient.
Observational
1 | years-old | <= |
12 | years-old | >= |
Female
Female patients who will be diagnosed with central precocious puberty (gonadotropin-dependent precocious puberty) at Department of Pediatrics, Showa University Hospital after July 2021.
1) premature thelarche
2) central precocious puberty with organic origin
3) gonadotropin-independent precocious puberty
100
1st name | Masanori |
Middle name | |
Last name | Adachi |
Showa University School of Medicine
Department of Pediatrics
142-8666
Hatanodai 1-5-8, Shinagawa-ku, Tokyo
03-3784-8565
m0adachi@med.showa-u.ac.jp
1st name | Masanori |
Middle name | |
Last name | Adachi |
Showa University School of Medicine
Department of Pediatrics
142-8666
Hatanodai 1-5-8, Shinagawa-ku, Tokyo
03-3784-8565
m0adachi@med.showa-u.ac.jp
Showa University
none
Self funding
SURAC, Showa University
Hatanodai 1-5-8, Shinagawa-ku, Tokyo
03-3784-8129
m-rinri@ofc.showa-u.ac.jp
NO
2021 | Year | 06 | Month | 03 | Day |
Unpublished
Open public recruiting
2021 | Year | 05 | Month | 12 | Day |
2021 | Year | 05 | Month | 12 | Day |
2021 | Year | 07 | Month | 01 | Day |
2030 | Year | 03 | Month | 31 | Day |
The observation period is as follows.
1) In the case of untreated follow-up, observation will be continued until menarche.
2) For cases treated with LHRH analog, observation will be continued 12 months after the end of treatment or until (re)start of menstruation.
2021 | Year | 06 | Month | 02 | Day |
2022 | Year | 06 | Month | 04 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000050542