Unique ID issued by UMIN | UMIN000043518 |
---|---|
Receipt number | R000049690 |
Scientific Title | Comparison of reversal with neostigmine vs. sugammadex for postoperative bowel function in patients undergoing colorectal surgery |
Date of disclosure of the study information | 2021/09/14 |
Last modified on | 2024/02/20 09:35:45 |
Comparison of reversal with neostigmine vs. sugammadex for postoperative bowel function in patients undergoing colorectal surgery
comparison of reversal with neostsigmine and sugammadex for post.op bowel function in patients undergoing colorectal surg.
Comparison of reversal with neostigmine vs. sugammadex for postoperative bowel function in patients undergoing colorectal surgery
comparison of reversal with neostsigmine and sugammadex for post.op bowel function in patients undergoing colorectal surg.
Asia(except Japan) |
colorectal surgery
Gastrointestinal surgery |
Others
NO
The purpose of this study was to investigate the difference in bowel function after surgery between the patients receiving neostigmine as a muscle relaxation reversal and those receiving sugammadex in patients undergoing colorectal surgery under general anesthesia.
Efficacy
Exploratory
Explanatory
Not applicable
Evaluating the time taken to expel gas in the first intestine after surgery
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Active
2
Treatment
Medicine |
sugammadex
neostigmine
19 | years-old | <= |
Not applicable |
Male and Female
1. Patients in the American Society of Anesthesiology class 1 and 2
2. Patients planning colorectal surgery under general anesthesia
3. Patients with prior consent to the study
1. Patients who have been given drugs that affect muscle relaxation recovery (anticonvulsants, antidepressants, etc.)
2. Patients who had history of neuromuscular diseases
3. Patients with hypersensitivity to rocuronium, neostigmine, and sugammadex
4. Patients with liver disease (OT/PT> 40 IU/L), kidney disease (Cr> 1.4 mg/dl)
5. Patients with with bowel obstruction
6. Patients who disagree with the test
122
1st name | JINWOO |
Middle name | |
Last name | PARK |
Seoul national university Bundang hospital
Anesthesiology and pain medicine
13620
82 Gumi-ro 173beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, Republic of Korea
+82317873640
jinul8282@snubh.org
1st name | JIYOUN |
Middle name | |
Last name | LEE |
Seoul national university Bundang hospital
Anesthesiology and pain medicine
13620
82 Gumi-ro 173beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, Republic of Korea
+82317873640
heykiki1@hanmail.net
self
MSD Korea Ltd.(MSD has decided to offer sugammadex drugs in-kind.)
Profit organization
Seoul national university Bundang hospital
172 Dolma-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, Republic of Korea
+82317878801
snubhirb@gmail.com
NO
2021 | Year | 09 | Month | 14 | Day |
Unpublished
Terminated
2020 | Year | 11 | Month | 01 | Day |
2021 | Year | 02 | Month | 26 | Day |
2022 | Year | 05 | Month | 12 | Day |
2023 | Year | 07 | Month | 07 | Day |
2021 | Year | 03 | Month | 04 | Day |
2024 | Year | 02 | Month | 20 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000049690
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |