Unique ID issued by UMIN | UMIN000043197 |
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Receipt number | R000049300 |
Scientific Title | Cardioprotective effects of angiotensin receptor-neprilysin inhibitors |
Date of disclosure of the study information | 2021/02/01 |
Last modified on | 2021/01/31 21:39:10 |
Cardioprotective effects of angiotensin receptor-neprilysin inhibitors in the real world
Cardioprotective effects of angiotensin receptor-neprilysin inhibitors in the real world
Cardioprotective effects of angiotensin receptor-neprilysin inhibitors
Cardioprotective effects of angiotensin receptor-neprilysin inhibitors
Japan |
Heart failure
Cardiology |
Others
NO
The purpose is whether the angiotensin receptor-neprilysin inhibitor(ARNI) administered by daily practice exerts cardioprotective effects.
Others
The purpose is to investigate the mechanisms by which the ARNI exerts its cardioprotective effects.
Confirmatory
Pragmatic
Not applicable
Change in NT-proBNP(BNP)(after 6 months or later)
Changes in troponin I(T), cardiac function(chest X-ray, electrocardiogram and echocardiography), renal function, inflammation, and the presence or absence of major cardiovascular events(MACE)(after 6 months or later)
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Patients undergoing treatment for heart failure in daily practice who are scheduled to change from angiotensin-converting enzyme inhibitors or angiotensin II receptor blocker to ARNI
Patients already receiving ARNI
Patients who do not change as a result of consideration
Patients with severe liver dysfunction (Child-Pugh classification C)
360
1st name | Shin-ichiro |
Middle name | |
Last name | Miura |
Fukuoka University Hospital
Department of Cardiology
814-0180
7-45-1 Nanakuma, Jonan-Ku, Fukuoka, Japan
0928011011
miuras@cis.fukuoka-u.ac.jp
1st name | Yuhei |
Middle name | Miura |
Last name | Shiga |
Fukuoka University Hospital
Department of Cardiology
8140180
7-45-1 Nanakuma, Jonan-Ku, Fukuoka, Japan
0928011011
yuheis@fukuoka-u.ac.jp
Department of Cardiology, Fukuoka University Hospital
Fukuoka University
Self funding
Murakami Karindoh Hospital, Hakujyuji Hospital, Fukuoka University Nishijin Hospital, Izumi General Medical Center, Yakuin Naika Junkanki Clinic
Fukuoka University Faculty of Medicine
7-45-1 Nanakuma, Jonan-Ku, Fukuoka, Japan
0928011011
fumed-ethics@fukuoka-u.ac.jp
NO
2021 | Year | 02 | Month | 01 | Day |
Unpublished
Enrolling by invitation
2020 | Year | 12 | Month | 23 | Day |
2021 | Year | 01 | Month | 13 | Day |
2021 | Year | 02 | Month | 01 | Day |
2026 | Year | 03 | Month | 31 | Day |
Observational study
2021 | Year | 01 | Month | 31 | Day |
2021 | Year | 01 | Month | 31 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000049300
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