Unique ID issued by UMIN | UMIN000042746 |
---|---|
Receipt number | R000048737 |
Scientific Title | Prospective observational study for the prediction of adverse events of triplet chemotherapy for pancreatic cancer and colorectal cancer by genetic polymorphisms. |
Date of disclosure of the study information | 2020/12/15 |
Last modified on | 2024/01/12 14:29:05 |
Prospective observational study for the prediction of adverse events of triplet chemotherapy for pancreatic cancer and colorectal cancer by genetic polymorphisms.
The prediction of adverse events of triplet chemotherapy for pancreatic cancer and colorectal cancer by genetic polymorphisms.
Prospective observational study for the prediction of adverse events of triplet chemotherapy for pancreatic cancer and colorectal cancer by genetic polymorphisms.
The prediction of adverse events of triplet chemotherapy for pancreatic cancer and colorectal cancer by genetic polymorphisms.
Japan |
pancreatic cancer and colorectal cancer
Gastrointestinal surgery | Hepato-biliary-pancreatic surgery |
Malignancy
YES
To analyze the predictors of adverse events of triplet chemotherapy for pancreatic cancer and colorectal cancer by genetic polymorphisms.
Others
The prediction of adverse events
Search for the predictors of adverse events
Search for the predictors of therapeutic effects
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Patients with pancreatic cancer and colorectal cancer (resectable or unresectable)in accordance with the following criteria
1)no gender
2)age over 20 years old
3)the patients who gained written consent by the patient's free will with sufficient understanding after receiving sufficient explanation for the participation of this study
4)the patients who are scheduled to receive or are undergoing any of the following treatments a) to c)
a)triplet chemotherapy (FOLFIRINOX therapy for pancreatic cancer or FOLFOXIRI therapy for colorectal cancer)
b)gemcitabine plus nab-PTX therapy for pancreatic cancer
c)FOLFIRI therapy or FOLFOX therapy for colorectal cancer
Nothing
150
1st name | Hiroaki |
Middle name | |
Last name | Nagano |
Yamaguchi University Graduate School of Medicine
Department of Gastroenterological, Breast and Endocrine Surgery
755-8505
1-1-1 Minami-Kogushi, Ube, Yamaguchi
0836-22-2264
hnagano@yamaguchi-u.ac.jp
1st name | Gen |
Middle name | |
Last name | Kanesada |
Yamaguchi University Graduate School of Medicine
Department of Gastroenterological, Breast and Endocrine Surgery
755-8505
1-1-1 Minami-Kogushi, Ube, Yamaguchi
0836-22-2264
gen021eb@yamaguchi-u.ac.jp
Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine
Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine
Self funding
Osaka International Cancer Institute
Center For Clinical Research, Yamaguchi University Hospital
1-1-1 Minami-Kogushi, Ube, Yamaguchi
0836-22-2428
me223@yamaguchi-u.ac.jp
NO
山口大学大学院 消化器・腫瘍外科学
2020 | Year | 12 | Month | 15 | Day |
Unpublished
Open public recruiting
2020 | Year | 11 | Month | 25 | Day |
2020 | Year | 11 | Month | 25 | Day |
2020 | Year | 12 | Month | 21 | Day |
2028 | Year | 03 | Month | 31 | Day |
Adverse events, including neutropenia, are frequently observed in patients undergoing triplet chemotherapy for pancreatic cancer and colorectal cancer. If it becomes possible to analyze the predictors of adverse events by genetic polymorphisms, we believe that it will lead to improvement of therapeutic effect.
2020 | Year | 12 | Month | 14 | Day |
2024 | Year | 01 | Month | 12 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000048737