UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000042692 |
|---|---|
| Receipt number | R000048721 |
| Scientific Title | Study of recurrent laryngeal papillomatosis by Single-cell transcriptomic analysis |
| Date of disclosure of the study information | 2020/12/10 |
| Last modified on | 2023/06/11 21:03:29 |
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Basic information
Public title
Study of recurrent laryngeal papillomatosis by Single-cell transcriptomic analysis
Acronym
Single-cell transcriptomic analysis for recurrent laryngeal papillomatosis
Scientific Title
Study of recurrent laryngeal papillomatosis by Single-cell transcriptomic analysis
Scientific Title:Acronym
Single-cell transcriptomic analysis for recurrent laryngeal papillomatosis
Region
| Japan |
Condition
Condition
Recurrent respiratory papillomatosis, recurrent laryngeal papillomatosis
Classification by specialty
| Oto-rhino-laryngology |
Classification by malignancy
Others
Genomic information
YES
Objectives
Narrative objectives1
The purpose of this study is to identify key cells/molecules related to progression of recurrent respiratory papillomatosis by single-cell transcriptomic analysis for the development of therapies.
Basic objectives2
Others
Basic objectives -Others
Pathological and molecular biological mechanisms
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Key cells and molecules related to progression of papillomatosis, tumor recurrence
Key secondary outcomes
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 20 | years-old | <= |
Age-upper limit
| 75 | years-old | > |
Gender
Male and Female
Key inclusion criteria
Diagnosed as recurrent respiratory papillomatosis or recurrent laryngeal papillomatosis
Provide written informed consent
Key exclusion criteria
Be concluded not eligible to enter the study by a principle investigator or sub-investigator.
Target sample size
20
Research contact person
Name of lead principal investigator
| 1st name | Rumi |
| Middle name | Ueha |
| Last name | Ueha |
Organization
The University of Tokyo
Division name
Swallowing Center
Zip code
113-8655
Address
7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan
TEL
03-3815-5411
UEHAR-OTO@h.u-tokyo.ac.jp
Public contact
Name of contact person
| 1st name | Rumi |
| Middle name | |
| Last name | Ueha |
Organization
The University of Tokyo
Division name
Swallowing Center
Zip code
113-8655
Address
7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan
TEL
03-3815-5411
Homepage URL
UEHAR-OTO@h.u-tokyo.ac.jp
Sponsor or person
Institute
The University of Tokyo
Institute
Department
Personal name
Funding Source
Organization
University Research Grants
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
the University of Tokyo
Address
7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan
Tel
03-5841-3600
hy-ohrs@m.u-tokyo.ac.jp
Secondary IDs
Secondary IDs
YES
Study ID_1
20011
Org. issuing International ID_1
Tokyo University of Science
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2020 | Year | 12 | Month | 10 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Open public recruiting
Date of protocol fixation
| 2020 | Year | 07 | Month | 27 | Day |
Date of IRB
| 2020 | Year | 07 | Month | 27 | Day |
Anticipated trial start date
| 2020 | Year | 12 | Month | 10 | Day |
Last follow-up date
| 2026 | Year | 03 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
The purpose of this study is to identify key cells/molecules (therapeutic targets) related to RRP progression for the development of therapies.
Management information
Registered date
| 2020 | Year | 12 | Month | 08 | Day |
Last modified on
| 2023 | Year | 06 | Month | 11 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000048721
