Unique ID issued by UMIN | UMIN000042523 |
---|---|
Receipt number | R000048543 |
Scientific Title | Efficacy of multiple gene panel testing for hereditary breast cancer and relevance to environmental factors |
Date of disclosure of the study information | 2021/02/01 |
Last modified on | 2020/11/24 00:30:42 |
Efficacy of multiple gene panel testing for hereditary breast cancer and relevance to environmental factors
Efficacy of multiple gene panel testing for hereditary breast cancer
Efficacy of multiple gene panel testing for hereditary breast cancer and relevance to environmental factors
Efficacy of multiple gene panel testing for hereditary breast cancer
Japan |
Hereditary breast cancer
Breast surgery |
Malignancy
YES
Improvement of detection rate of pathogenic variant
Improvement of 5 years overall survival rate
Relationship between mutation of moderate risk gene and environmental factors
Efficacy
Detection rate of pathogenic variant
5 years overall survival rate
Relationship between mutation of moderate risk gene and environmental factors
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine | Device,equipment | Maneuver |
mammography MRI annual
chemotherapy for six months
DNA damaging agents
Radiotherapy omission
Prophylactic Surgery mastectomy oophorectomy
20 | years-old | <= |
70 | years-old | > |
Male and Female
Breast cancer meeting the criteria of genetic testing for BRCA1/2, TP53, PTEN, CDH1, or STK11
The patient judged as inappropriate by responsible doctor
10
1st name | Hiroyuki |
Middle name | |
Last name | Maeda |
Faculty of medicine, University of Fukui
First Department of Surgery
910-1193
23-3, Matsuoka, Shimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui
0776613111
maedah@u-fukui.ac.jp
1st name | Hiroyuki |
Middle name | |
Last name | Maeda |
Faculty of medicine, University of Fukui
First Department of Surgery
910-1193
23-3, Matsuoka, Shimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui
0776613111
maedah@u-fukui.ac.jp
University of Fukui
University of Fukui
Other
Medical Research Support Center, Fukui University Hospital
23-3, Matsuoka, Shimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui
0776618529
chiken@ml.u-fukui.ac.jp
NO
2021 | Year | 02 | Month | 01 | Day |
Unpublished
Enrolling by invitation
2021 | Year | 01 | Month | 12 | Day |
2021 | Year | 01 | Month | 12 | Day |
2021 | Year | 02 | Month | 01 | Day |
2027 | Year | 03 | Month | 31 | Day |
2020 | Year | 11 | Month | 24 | Day |
2020 | Year | 11 | Month | 24 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000048543