UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000060875 |
|---|---|
| Receipt number | R000048517 |
| Scientific Title | Symmetry Preference and Psychiatric Symptoms |
| Date of disclosure of the study information | 2026/03/16 |
| Last modified on | 2026/03/09 17:17:51 |
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Basic information
Public title
Symmetry Preference and Psychiatric Symptoms
Acronym
Symmetry Preference and Psychiatric Symptoms
Scientific Title
Symmetry Preference and Psychiatric Symptoms
Scientific Title:Acronym
Symmetry Preference and Psychiatric Symptoms
Region
| Japan |
Condition
Condition
Schizophrenic Patients, Healthy Individuals
Classification by specialty
| Psychiatry | Adult |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
We examine the symmetry preference of schizophrenic Patients and Healthy Individuals using the figures and baum-test.
We examine the symmetry preference of schizophrenic patients
Basic objectives2
Others
Basic objectives -Others
We examine the preference of schizophrenic patients using eye camera.
Trial characteristics_1
Others
Trial characteristics_2
Others
Developmental phase
Not applicable
Assessment
Primary outcomes
Frequencies for Symmetrical Figures
Key secondary outcomes
Positive and Negative Syndrome Scale (Schizophrenic Patients)
baum-test
Eye Movements
Neo Five Factor Inventory
Profile of Mood States
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 20 | years-old | <= |
Age-upper limit
| 80 | years-old | >= |
Gender
Male and Female
Key inclusion criteria
Schizophrenic Patients who were diagnosed according to DSM
Healthy Adults in University and Hospital
Key exclusion criteria
other than those abouve
Target sample size
160
Research contact person
Name of lead principal investigator
| 1st name | Yumi |
| Middle name | |
| Last name | Iwamitsu |
Organization
Kitasato University
Division name
Graduate School of Medical Sciences
Zip code
2520373
Address
1-15-1 Kitasato, Minami, Sagamihara
TEL
042-778-7961
iyumi@kitasato-u.ac.jp
Public contact
Name of contact person
| 1st name | Yumi |
| Middle name | |
| Last name | Iwamitsu |
Organization
Kitasato University
Division name
Graduate School of Medical Sciences
Zip code
2520373
Address
1-15-1 Kitasato, Minami, Sagamihara
TEL
042-778-7961
Homepage URL
iyumi@kitasato-u.ac.jp
Sponsor or person
Institute
Kitasato University
Institute
Department
Personal name
Funding Source
Organization
Grants in Aid for Scientific Research
Organization
Division
Category of Funding Organization
Japanese Governmental office
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Kitasato University
Address
1-15-1 Kitasato, Minami, Sagamihara
Tel
042-778-9601
iyumi@kitasato-u.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
鶴賀病院(長野県）、早稲田大学（東京都）
Other administrative information
Date of disclosure of the study information
| 2026 | Year | 03 | Month | 16 | Day |
Related information
URL releasing protocol
https://sites.google.com/view/sem-takemura/%E7%A0%94%E7%A9%B6%E3%83%86%E3%83%BC%E3%83%9E%E5%B1%A5%E6
Publication of results
Partially published
Result
URL related to results and publications
https://doi.org/10.11477/mf.1405206432
Number of participants that the trial has enrolled
127
Results
It became clear that patients with schizophrenia showed a higher frequency of preference for symmetry compared to healthy individuals. A positive correlation was observed between schizophrenia patients' symmetry preference and both negative and positive symptoms, while a negative correlation was found with the general psychopathology scale. Analysis of the data from eye camera is currently underway.
Results date posted
| 2026 | Year | 03 | Month | 09 | Day |
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Patients with schizophrenia: Participants included outpatients and inpatients at Hospital A's psychiatric department diagnosed with schizophrenia based on DSM-IV-TR criteria and deemed eligible for the study by their attending physician.
Healthy individuals: University students, graduate students, and hospital staff who applied to participate after seeing the study recruitment poster. The ages were matched to patients with schizophrenia.
Participant flow
Patients with schizophrenia: The study was conducted in a one-on-one face-to-face format in an interview room. After completing the figure- splitting task, participants were verbally asked about their impressions of the drawing. Subsequently, the attending physician assessed psychiatric symptoms using the PANSS. When using the eye camera, participants wore the device, viewed the stimulus presented on the display for each trial, and performed the figure-splitting task by moving the dividing line using a touch pen.
Healthy controls: The study was conducted in a one-on-one face-to-face format in university conference rooms or private rooms. After completing the figure-splitting task, participants were asked to anonymously fill out a specially designed questionnaire with basic attributes and their impressions of the drawing. When using the eye camera, participants wore the device, viewed the stimulus presented on the display for each trial, and performed the figure-splitting task by moving the dividing line using a touch pen.
Adverse events
No adverse events have been reported.
Outcome measures
Frequencies for Symmetrical Figures
Positive and Negative Syndrome Scale (Schizophrenic Patients)
baum-test
Eye Movements
Neo Five Factor Inventory
Profile of Mood States
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
No longer recruiting
Date of protocol fixation
| 2015 | Year | 03 | Month | 25 | Day |
Date of IRB
| 2015 | Year | 03 | Month | 25 | Day |
Anticipated trial start date
| 2015 | Year | 03 | Month | 25 | Day |
Last follow-up date
| 2020 | Year | 07 | Month | 20 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
Healthy subjects: University students, graduate students, and staff who applied to participate through poster display and gave their consent to participate in the study.
Patients: Psychiatric outpatients and inpatients diagnosed with schizophrenia according to ICD-10, whose attending physicians have determined that they are eligible to participate in the study and who have given written consent (20 years of age or older).
Management information
Registered date
| 2026 | Year | 03 | Month | 09 | Day |
Last modified on
| 2026 | Year | 03 | Month | 09 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000048517
