Unique ID issued by UMIN | UMIN000042006 |
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Receipt number | R000047941 |
Scientific Title | Plaque progression from normal vessel wall to fibroatheroma: lessons from over 5-year follow-up optical coherence tomography study |
Date of disclosure of the study information | 2020/11/01 |
Last modified on | 2020/10/05 00:22:39 |
Plaque progression from normal vessel wall to fibroatheroma: lessons from over 5-year follow-up optical coherence tomography study
Plaque progression from normal vessel wall to fibroatheroma
Plaque progression from normal vessel wall to fibroatheroma: lessons from over 5-year follow-up optical coherence tomography study
Plaque progression from normal vessel wall to fibroatheroma
Japan |
coronary artery disease
Cardiology |
Others
NO
to investigate the incidence and related factors associated with atherosclerotic progression from normal vessel wall (NVW) to fibroatheroma
Others
The objective of the present study is to investigate the incidence and related factors associated with atherosclerotic progression from NVW to fibroatheroma using long-term serial OCT follow-up data over 5 years.
Not applicable
Presence of atheroma progression between Baseline and Follow-up
Baseline OCT findings and atheroma progression
Serial changes of the intimal thickness during the follow-up period
Observational
Not applicable |
Not applicable |
Male and Female
The patients who underwent OCT imaging for native coronary artery were screened, we enrolled the patients who met the following inclusion and exclusion criteria into the present study. The inclusion criteria included patients 1) who underwent serial OCT imaging for native coronary artery over 5 years; 2) who underwent OCT for early atherosclerotic lesions located >5mm away from the stent edges, defined as diameter stenosis <30% on coronary angiography
The exclusion criteria included patients 1) who had undergone bypass graft surgery; 2) with chronic total occlusion lesions within the target vessel; 3) with poor OCT images; 4) who had undergone coronary revascularization within the same vessel during the follow-up period.
49
1st name | Hiromasa |
Middle name | |
Last name | Otake |
Department of Internal Medicine, Kobe University Graduate School of Medicine
Division of Cardiovascular Medicine
6500017
7-5-2 Kusunoki-cho, Chuo-ku, Kobe, Hyogo
078-382-5846
hotake@med.kobe-u.ac.jp
1st name | Ryo |
Middle name | |
Last name | Takeshige |
Department of Internal Medicine, Kobe University Graduate School of Medicine
Division of cardiology
6500017
7-5-2 Kusunoki-cho, Chuo-ku, Kobe, Hyogo
078-382-5846
takeshige.kobe@gmail.com
Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
Other
Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
7-5-2 Kusunoki-cho, Chuo-ku, Kobe, Hyogo
078-382-5846
takeshige.kobe@gmail.com
NO
2020 | Year | 11 | Month | 01 | Day |
Unpublished
49
Completed
2020 | Year | 08 | Month | 01 | Day |
2020 | Year | 10 | Month | 12 | Day |
2020 | Year | 08 | Month | 01 | Day |
2022 | Year | 03 | Month | 31 | Day |
Baseline OCT images were evaluated every 1mm slice. Then, matched follow-up OCT images were selected. The cross-sections were diagnosed as Progression when NVW in the cross-section reduced by >30 degrees from baseline OCT to >5-year follow-up OCT. We investigated the incidence and related factors associated with atherosclerotic progression from NVW to fibroatheroma using long-term serial OCT follow-up data over 5 years.
2020 | Year | 10 | Month | 05 | Day |
2020 | Year | 10 | Month | 05 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000047941
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