Unique ID issued by UMIN | UMIN000041786 |
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Receipt number | R000047693 |
Scientific Title | Monitoring of KRAS-mutated cell-free DNA in pancreatic cancer patients with neoadjuvant treatment |
Date of disclosure of the study information | 2020/11/01 |
Last modified on | 2020/09/14 14:44:56 |
Monitoring of KRAS-mutated circulating tumor DNA in pancreatic cancer patients with neoadjuvant treatment
Monitoring of ctDNA in pancreatic cancer
Monitoring of KRAS-mutated cell-free DNA in pancreatic cancer patients with neoadjuvant treatment
Monitoring of ctDNA in pancreatic cancer
Japan |
pancreatic ductal adenocarcinoma
Hematology and clinical oncology | Hepato-biliary-pancreatic surgery |
Malignancy
NO
To investigate the impact of KRAS-mutated cell-free DNA on the clinical course of pancreatic ductal adenocarcinoma
Efficacy
Disease free survival on 6 months after surgery
-Overall survival
-Disease free survival
-R0 resection
-Serum CA19-9
-Pathological response
Observational
20 | years-old | <= |
Not applicable |
Male and Female
-Histologically confirmed pancreatic ductal adenocarcinoma
-Planned for neoadjuvant treatment
-ECOG performance status 0 or 1
-No history of any treatment for pancreatic ductal adenocarcinoma
-Administration of immunosuppressive agent
-Severe organ dysfunction
-Severe infection
-Pregnancy
-Double cancer
-Investigator judgement that the patient should not participate for any reason.
30
1st name | Horochika |
Middle name | |
Last name | Toyama |
Kobe University Hospital
Hepato-Biliary-Pancreatic Surgery
6500017
7-5-2 Kusunoki-cho Chuo-ku Kobe
078-382-6302
toyama@med.kobe-u.ac.jp
1st name | Sachiyo |
Middle name | |
Last name | Shirakawa |
Kobe University Hospital
Hepato-Biliary-Pancreatic Surgery
650017
7-5-2 Kusunoki-cho Chuo-ku Kobe
078-382-6302
sachiyo@pearl.kobe-u.ac.jp
Kobe University
Kobe University Hospital
Self funding
Medical ethics committee of Kobe University
7-5-2 Kusunoki-cho Chuo-ku Kobe
078-382-6999
k9shien@med.kobe-u.ac.jp
NO
神戸大学病院
2020 | Year | 11 | Month | 01 | Day |
Unpublished
Preinitiation
2020 | Year | 10 | Month | 09 | Day |
2020 | Year | 11 | Month | 15 | Day |
2025 | Year | 12 | Month | 31 | Day |
Observational study
2020 | Year | 09 | Month | 14 | Day |
2020 | Year | 09 | Month | 14 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000047693
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