Unique ID issued by UMIN | UMIN000041279 |
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Receipt number | R000047145 |
Scientific Title | Study on the association between AGEs and sleep apnea syndrome in patients with type 2 diabetes mellitus |
Date of disclosure of the study information | 2020/08/02 |
Last modified on | 2023/02/08 15:40:03 |
Study on the association between AGEs and sleep apnea syndrome in patients with type 2 diabetes mellitus
Study on the association between AGEs and sleep apnea syndrome in patients with type 2 diabetes mellitus
Study on the association between AGEs and sleep apnea syndrome in patients with type 2 diabetes mellitus
Study on the association between AGEs and sleep apnea syndrome in patients with type 2 diabetes mellitus
Japan |
Type 2 Diabetes mellitus
Endocrinology and Metabolism |
Others
NO
The purpose of this study was to determine the relationship between skin autofluorescence(skin AF) and clinical context and to clarify the association between skin autofluorescence and sleep apnea syndrome by measuring skin autofluorescence and performing a watch PAT in patients with type 2 diabetes.
Efficacy
Correlation between skin AF and AHI measured by watch PAT.
1.Correlation of PSQI, ESS, NoSAS score and No-apnea score with skin AF.
2.Correlation of PSQI, ESS, NoSAS score and No-apnea score with AHI measured by watch PAT.
3.Correlation of carotid artery echocardiography, Endo PAT, ABI, baPWV, CAVI and other macrovascular diseases, body composition analysis, and microvascular diseases with skin AF.
4.Correlation of carotid artery echocardiography, Endo PAT, ABI, baPWV, CAVI and other macrovascular diseases, body composition analysis, and microvascular diseases with AHI measured by watch PAT.
Observational
20 | years-old | <= |
Not applicable |
Male and Female
(1) Patients with a diagnosis of type 2 diabetes at the time of obtaining consent
(2) Patients who were 20 years of age or older at the time of obtaining consent
(3) The participant himself or herself is fully informed about the research and agrees in writing.
(4) Any gender
(1) Patients using CPAP for the diagnosis of obstructive sleep apnea syndrome
(2) After extreme sunburn
(3) Serious infections, currently being treated for a carrier cancer (can be included if the patient is in remission and being followed up), serious respiratory disease,serious trauma, serious neurological or autonomic disorders, hyperthyroidism or hypothyroidism(can be included if under treatment and under control)
(4) Type 1 diabetes patients
(5) Pregnant patients
(6) Patients on dialysis
(7) Patients with persistent non-sinus arrhythmias
(8) Patients with pacemaker implantation
(9) Patients taking an alpha-blocker
(10) Patients undergoing treatment with steroids (oral or injectable)
(11) Patients with craniofacial abnormalities.
(12) Other items deemed inappropriate by the physician in charge
(13)Patients refused to participate in the study by blanket consent
100
1st name | Tadashi |
Middle name | |
Last name | Yamakawa |
Yokohama City University Medical Center
Department of endocrinology & metabolism
232-0024
4-57, Urahunecho, Minami-ku, Yokohama-shi, Kanagawa, 232-0024, Japan
045-261-5656
yamakat@yokohama-cu.ac.jp
1st name | Masahiro |
Middle name | |
Last name | Ichikawa |
Yokohama City University Medical Center
Department of endocrinology & metabolism
232-0024
4-57, Urahunecho, Minami-ku, Yokohama-shi, Kanagawa, 232-0024, Japan
045-261-5656
t196009c@yokohama-cu.ac.jp
Yokohama City University Medical Center
None
Self funding
Yokohama City University Certified Institutional Review Board
3-9 Fukuura, Kanazawa-ku, Yokohama, Japan
0453707627
rinri@yokohama-cu.ac.jp
NO
横浜市立大学附属市民総合医療センター
2020 | Year | 08 | Month | 02 | Day |
Unpublished
Completed
2020 | Year | 07 | Month | 08 | Day |
2020 | Year | 07 | Month | 29 | Day |
2020 | Year | 08 | Month | 02 | Day |
2023 | Year | 09 | Month | 30 | Day |
We will collect information from the medical record, including background and history, collected at the time of obtaining consent or previously from patients with type 2 diabetes who are in or outpatients. We will measure blood and skin AF. We will perform a watch PAT to assess the AHI for sleep apnea syndrome. We will evaluate other complications within the scope of practice (EKG, carotid echocardiogram, fundus examination, ABI, baPWV, CAVI, Endo pat, body composition analysis, etc.).
2020 | Year | 08 | Month | 02 | Day |
2023 | Year | 02 | Month | 08 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000047145
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