Unique ID issued by UMIN | UMIN000040786 |
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Receipt number | R000046575 |
Scientific Title | Analysis of the dynamic change of platelet before and after cardiac surgery |
Date of disclosure of the study information | 2020/06/16 |
Last modified on | 2020/06/16 16:17:58 |
The change of platelet by cardiac surgery
The change of platelet by cardiac surgery
Analysis of the dynamic change of platelet before and after cardiac surgery
Analysis of the dynamic change of platelet before and after cardiac surgery
Japan |
cardiac diseases
Cardiovascular surgery |
Others
NO
We analyze the chronological change of platelet proteins, peptides, and small RNAs before and after cardiac surgery.
Others
We identify the platelet proteins, peptides, and small RNAs altered by cardiac surgery.
Exploratory
Pragmatic
Not applicable
Vascular endothelial growth factor (VEGF) in serum: From just before cardiac surgery to one month after surgery.
MicroRNAs in serum and platelets.
IL-6 and thrombopoietin (TPO) in serum.C-reactive protein (CRP) and Brain natriuretic peptide (BNP) in serum.
Observational
Not applicable |
Not applicable |
Male and Female
Patients with cardiac surgery.
Patients with dialysis
100
1st name | Yutaka |
Middle name | |
Last name | Imoto |
Kagoshima University Graduate School of Medical and Dental Sciences
Department of Cardiovascular and Gastroenterological Surgery
890-8520
8-35-1 Sakuragaoka, Kagoshima
099-275-5368
imoto@m3.kufm.kagoshima-u.ac.jp
1st name | Teruto |
Middle name | |
Last name | Hashiguchi |
Kagoshima University Graduate School of Medical and Dental Sciences
Department of Laboratory and Vascular Medicine
890-8520
8-35-1 Sakuragaoka, Kagoshima
099-275-5437
terutoha@m3.kufm.kagoshima-u.ac.jp
Kagoshima University Hospital
Kagoshima University Graduate School of Medical and Dental Sciences
Other
Kagoshima Medical Center
The research ethics committees of Kagoshima University Hospital
8-35-1 Sakuragaoka, Kagoshima
099-275-6692
crmc@m2.kufm.kagoshima-u.ac.jp
NO
2020 | Year | 06 | Month | 16 | Day |
https://com4.kufm.kagoshima-u.ac.jp/department/015-2/015-6/
Unpublished
N/A
98
Elevation of intra-platelet VEGF-A and miR-126 were observed after cardiac surgery.
2020 | Year | 06 | Month | 16 | Day |
Male patients shared 95%. Patients with hypertension, or diabetes, or peripheral artery disease, represented 85%, 50%, and 12%, respectively.
All participants attended this study after administration of Kagoshima University Hospital and providing written informed consents.
N/A
IL-6 and TPO in serum, miR-126 and VEGF in serum and platelet, were measured. The data from the routine blood tests, complete blood counts and biochemical blood test, were referred.
Completed
2013 | Year | 12 | Month | 27 | Day |
2013 | Year | 12 | Month | 27 | Day |
2014 | Year | 01 | Month | 01 | Day |
2015 | Year | 03 | Month | 31 | Day |
Ninety eight patients were registered and analyzed.
2020 | Year | 06 | Month | 16 | Day |
2020 | Year | 06 | Month | 16 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000046575
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