Unique ID issued by UMIN | UMIN000040747 |
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Receipt number | R000046521 |
Scientific Title | The investigation of the relationship between coronary atherosclerosis and clinical data |
Date of disclosure of the study information | 2020/06/15 |
Last modified on | 2020/12/13 09:32:04 |
The investigation of the relationship between coronary atherosclerosis and clinical data
Coronary artery plaque analysis
The investigation of the relationship between coronary atherosclerosis and clinical data
Analysis of coronary atherosclerosis by single cell RNA sequencing
Japan |
Coronary atherosclerosis
Medicine in general | Cardiology |
Others
NO
To clarify the difference of characterization between stable and unstable coronary atherosclerosis by single-cell RNA sequencing
Others
Elucidation of the mechanism of the development of arterial sclerosis
Cluster analysis of single-cell RNA sequencing and cluster analysis of gene expression variation in each cluster on both stable and unstable coronary atherosclerosis
Relationship between plaque assessment collected by DCA and various plaque data
1.Plaque evaluation by CT
2.Plaque assessment by cMRI
3. Bulk RNA sequencing
4. microRNA sequencing
5. Histological evaluation
Observational
20 | years-old | <= |
Not applicable |
Male and Female
(1) Patients 20 years of age or older at the time of percutaneous coronary intervention(PCI)
(2) Patients who underwent PCI with directional coronary atherectomy and had a plaque collected
(3) Patients for whom written consent has been obtained by the individual
(1) Patients taking steroids, autoimmune diseases, undergoing treatment for cancer, or suffering from hepatitis B and C viruses
(2) Other patients who are deemed inappropriate by the physician in charge of the study.
60
1st name | Tomoya |
Middle name | |
Last name | Yamashita |
Kobe University Hospital
The division of Cardiovascular medicine
650-0017
7-5-2, Kusunoki-cho, Kobe, Japan
078-382-5111
tomoya@med.kobe-u.ac.jp
1st name | Hiroyuki |
Middle name | |
Last name | Yamamoto |
Hyogo Brain and Heart Centor
The division of Cardiovascular medicine
6700981
Kou-Saisyo520, Himeji, Hyogo, Japan
079-293-3131
y0493589m@hotmail.co.jp
Hyogo Brain and Heart Centor
Kobe University Hospital
Kobe University Hospital
Self funding
Kobe University Hospital
7-5-2, Kusunoki-cho, Kobe, Japan
078-382-5111
chiken@med.kobe-u.ac.jp
NO
2020 | Year | 06 | Month | 15 | Day |
Unpublished
Open public recruiting
2020 | Year | 05 | Month | 31 | Day |
2020 | Year | 10 | Month | 22 | Day |
2020 | Year | 10 | Month | 22 | Day |
2023 | Year | 03 | Month | 31 | Day |
Prospective observational study
2020 | Year | 06 | Month | 13 | Day |
2020 | Year | 12 | Month | 13 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000046521
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