UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000040181 |
|---|---|
| Receipt number | R000045810 |
| Scientific Title | An integrated multi-omics study of tumor heterogeneity in patients with treatment-resistant malignant cancer |
| Date of disclosure of the study information | 2020/04/16 |
| Last modified on | 2023/09/16 09:51:40 |
* This page includes information on clinical trials registered in UMIN clinical trial registed system.
* We don't aim to advertise certain products or treatments
Basic information
Public title
An integrated multi-omics study of tumor heterogeneity in patients with treatment-resistant malignant cancer
Acronym
A study of tumor heterogeneity in patients with treatment-resistant malignant cancer
Scientific Title
An integrated multi-omics study of tumor heterogeneity in patients with treatment-resistant malignant cancer
Scientific Title:Acronym
A study of tumor heterogeneity in patients with treatment-resistant malignant cancer
Region
| Japan |
Condition
Condition
malignant cancer
Classification by specialty
| Hematology and clinical oncology |
Classification by malignancy
Malignancy
Genomic information
YES
Objectives
Narrative objectives1
To reveal the molecular heterogeneity in patients with treatment-resistant malignant cancer
Basic objectives2
Others
Basic objectives -Others
Identification of biomarkers predicting therapeutic resistance
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
1. Gene alterations by DNA sequence
2. Gene expression and fusion genes by tarRNA sequence
3. Epigenomic alterations by micro-array
Key secondary outcomes
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| Not applicable |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
Patients who agree with the content of this study and submit the written consent form
Key exclusion criteria
Other than those above
Target sample size
100
Research contact person
Name of lead principal investigator
| 1st name | Jumpei |
| Middle name | |
| Last name | Takeshita |
Organization
Kansai Electric Power Hospital
Division name
Department of Oncology
Zip code
553-0003
Address
2-1-7Fukushima,Fukushima-ku,Osaka
TEL
0664585821
takeshita.jumpei@e4.kepco.co.jp
Public contact
Name of contact person
| 1st name | Jumpei |
| Middle name | |
| Last name | Takeshita |
Organization
Kansai Electric Power Hospital
Division name
Department of Oncology
Zip code
553-0003
Address
2-1-7Fukushima,Fukushima-ku,Osaka
TEL
0664585821
Homepage URL
takeshita.jumpei@e4.kepco.co.jp
Sponsor or person
Institute
Kansai Electric Power Hospital
Institute
Department
Personal name
Funding Source
Organization
Kansai Electric Power Hospital
Organization
Division
Category of Funding Organization
Other
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Kansai Electric Power Hospital
Address
2-1-7Fukushima,Fukushima-ku,Osaka
Tel
0664585821
koga.kazuhiro@c3.kepco.co.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2020 | Year | 04 | Month | 16 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Completed
Date of protocol fixation
| 2020 | Year | 04 | Month | 10 | Day |
Date of IRB
| 2020 | Year | 04 | Month | 10 | Day |
Anticipated trial start date
| 2020 | Year | 04 | Month | 16 | Day |
Last follow-up date
| 2025 | Year | 04 | Month | 16 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
Prospective study
Management information
Registered date
| 2020 | Year | 04 | Month | 16 | Day |
Last modified on
| 2023 | Year | 09 | Month | 16 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000045810
